Les Inscriptions à la Bibliothèque sont ouvertes en
ligne via le site: https://biblio.enp.edu.dz
Les Réinscriptions se font à :
• La Bibliothèque Annexe pour les étudiants en
2ème Année CPST
• La Bibliothèque Centrale pour les étudiants en Spécialités
A partir de cette page vous pouvez :
Retourner au premier écran avec les recherches... |
Détail de l'indexation
D000118
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Ouvrages de la bibliothèque en indexation D000118
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Effets des derivees de la chitine, des composes spiro et des derives coumariniques sur des lignees cancereuses humaines / Mustapha Mounir Bouhenna
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Titre : Effets des derivees de la chitine, des composes spiro et des derives coumariniques sur des lignees cancereuses humaines Type de document : texte imprimé Auteurs : Mustapha Mounir Bouhenna, Auteur ; Grib, Hocine, Directeur de thèse Editeur : [S.l.] : [s.n.] Année de publication : 2018 Importance : 164 f. Présentation : ill. Format : 30 cm Accompagnement : 1 CD-ROM. Note générale : Thèse de Doctorat : Génie de l'Environnement : Alger, École Nationale Polytechnique : 2018
Bibliogr. f. 142 - 164Langues : Français (fre) Mots-clés : Activité anti-tumorale ; Apoptose ; Derivés coumariniques ; Cytotoxicité ; XCELLIGENCE. Index. décimale : D000118 Résumé : Dans ce travail, l’effet anti cancéreux des dérivés de la chitine: le chitosane et les chitosaneoligosaccharides, ainsi que celui de deux groupes de molécules synthétisées chimiquement: un premier groupe de six molécules spiro [lactone-cyclohexanone] 4-9 et un deuxième groupe de neuf dérivés chromone et coumarin (1-9), a été évalué envers différentes lignées cancéreuses humaines. Les résultats ont montré que les composés spiro 4 et 9 affectaient significativement la viabilité et la prolifération des lignées cellulaires K562 et U937. Le composé 4 a montré un potentiel d’inhibition de l’activation du NF-kB induite par le TNFα d’une manière dose-dépendante. Les composés 1,2,8 et 9 ont montré le potentiel d’inhibition de la prolifération des lignées cellulaires le plus intéressant parmi le groupe des dérivés chromone et coumarine. Le composé 8 a induit la mort cellulaire par apoptose aux cellules HCT-116, d'une manière dépendante de la dose et du temps, comme on peut le constater avec les résultats de la cytométrie en flux et du Western blot. Effets des derivees de la chitine, des composes spiro et des derives coumariniques sur des lignees cancereuses humaines [texte imprimé] / Mustapha Mounir Bouhenna, Auteur ; Grib, Hocine, Directeur de thèse . - [S.l.] : [s.n.], 2018 . - 164 f. : ill. ; 30 cm + 1 CD-ROM.
Thèse de Doctorat : Génie de l'Environnement : Alger, École Nationale Polytechnique : 2018
Bibliogr. f. 142 - 164
Langues : Français (fre)
Mots-clés : Activité anti-tumorale ; Apoptose ; Derivés coumariniques ; Cytotoxicité ; XCELLIGENCE. Index. décimale : D000118 Résumé : Dans ce travail, l’effet anti cancéreux des dérivés de la chitine: le chitosane et les chitosaneoligosaccharides, ainsi que celui de deux groupes de molécules synthétisées chimiquement: un premier groupe de six molécules spiro [lactone-cyclohexanone] 4-9 et un deuxième groupe de neuf dérivés chromone et coumarin (1-9), a été évalué envers différentes lignées cancéreuses humaines. Les résultats ont montré que les composés spiro 4 et 9 affectaient significativement la viabilité et la prolifération des lignées cellulaires K562 et U937. Le composé 4 a montré un potentiel d’inhibition de l’activation du NF-kB induite par le TNFα d’une manière dose-dépendante. Les composés 1,2,8 et 9 ont montré le potentiel d’inhibition de la prolifération des lignées cellulaires le plus intéressant parmi le groupe des dérivés chromone et coumarine. Le composé 8 a induit la mort cellulaire par apoptose aux cellules HCT-116, d'une manière dépendante de la dose et du temps, comme on peut le constater avec les résultats de la cytométrie en flux et du Western blot. Exemplaires
Code-barres Cote Support Localisation Section Disponibilité Spécialité Etat_Exemplaire T000086 D000118 Périodique Bibliothèque Annexe Thèse de Doctorat Disponible Consultation sur place T000085 D000118 Papier Bibliothèque centrale Thèse de Doctorat Disponible Consultation sur place Documents numériques
BOUHENNA.Mustapha..pdfURL