Dépouillements

Biomimetic materials in tissue engineering / Jennifer Patterson in Materials today, Vol. 13 N° 1-2 (Janvier/Fevrier 2010) 

Public ISBD [article]  in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 14–22 Titre : Biomimetic materials in tissue engineering Type de document : texte imprimé Auteurs : Jennifer Patterson, Auteur ; Mikaël M. Martino, Auteur ; Jeffrey A. Hubbell, Auteur Année de publication : 2010 Article en page(s) : pp. 14–22 Note générale : Ingénierie Langues : Anglais (eng) Mots-clés : Molecules  Biomolecules  Biomimetic  materials  Chemical  schemes  Tissue  engineering Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Biomaterial matrices are being developed that mimic the key characteristics of the extracellular matrix, including presenting adhesion sites and displaying growth factors in the context of a viscoelastic hydrogel. This review focuses on two classes of materials: those that are derived from naturally occurring molecules and those that recapitulate key motifs of biomolecules within biologically active synthetic materials. For biologically derived materials, methods are being sought to gain molecular-level control over biological characteristics and biomechanics. For synthetic, biomimetic materials, chemical schemes are being developed to enable in situ cross-linking and protease-dependent degradation and release of incorporated growth factors. These materials will open new doors to biosurgical therapeutics in tissue engineering and regenerative medicine. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700134 [article] Biomimetic materials in tissue engineering [texte imprimé] / Jennifer Patterson, Auteur ; Mikaël M. Martino, Auteur ; Jeffrey A. Hubbell, Auteur . - 2010 . - pp. 14–22. Ingénierie Langues : Anglais (eng) in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 14–22 Mots-clés : Molecules  Biomolecules  Biomimetic  materials  Chemical  schemes  Tissue  engineering Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Biomaterial matrices are being developed that mimic the key characteristics of the extracellular matrix, including presenting adhesion sites and displaying growth factors in the context of a viscoelastic hydrogel. This review focuses on two classes of materials: those that are derived from naturally occurring molecules and those that recapitulate key motifs of biomolecules within biologically active synthetic materials. For biologically derived materials, methods are being sought to gain molecular-level control over biological characteristics and biomechanics. For synthetic, biomimetic materials, chemical schemes are being developed to enable in situ cross-linking and protease-dependent degradation and release of incorporated growth factors. These materials will open new doors to biosurgical therapeutics in tissue engineering and regenerative medicine. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700134

Resorbable biomaterials as bone graft substitutes / Marc Bohner in Materials today, Vol. 13 N° 1-2 (Janvier/Fevrier 2010) 

Public ISBD [article]  in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 24–30 Titre : Resorbable biomaterials as bone graft substitutes Type de document : texte imprimé Auteurs : Marc Bohner, Auteur Année de publication : 2010 Article en page(s) : pp. 24–30 Note générale : Ingénierie Langues : Anglais (eng) Mots-clés : Biomaterials  Graft  substitutes  materials  Metals  Polymers  Cements  Resorbable  materials Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : An ageing population and the democratization of high-risk sports have led to a surge of bone-related diseases and bone fractures. As a result, the use of bone graft substitutes has dramatically increased in the last decade. A wide range of materials are considered, from metals to polymers, from injectable cements to complex porous solids. This article aims at presenting a concise, accessible overview of the field of resorbable bone graft substitute materials. A slight emphasis is set on synthetic materials, in particular calcium phosphates. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700146 [article] Resorbable biomaterials as bone graft substitutes [texte imprimé] / Marc Bohner, Auteur . - 2010 . - pp. 24–30. Ingénierie Langues : Anglais (eng) in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 24–30 Mots-clés : Biomaterials  Graft  substitutes  materials  Metals  Polymers  Cements  Resorbable  materials Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : An ageing population and the democratization of high-risk sports have led to a surge of bone-related diseases and bone fractures. As a result, the use of bone graft substitutes has dramatically increased in the last decade. A wide range of materials are considered, from metals to polymers, from injectable cements to complex porous solids. This article aims at presenting a concise, accessible overview of the field of resorbable bone graft substitute materials. A slight emphasis is set on synthetic materials, in particular calcium phosphates. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700146

Replication of the 3D architecture of tissues / R. Perez-Castillejos in Materials today, Vol. 13 N° 1-2 (Janvier/Fevrier 2010) 

Public ISBD [article]  in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 32–41 Titre : Replication of the 3D architecture of tissues Type de document : texte imprimé Auteurs : R. Perez-Castillejos, Auteur Année de publication : 2010 Article en page(s) : pp. 32–41 Note générale : Ingénierie Langues : Anglais (eng) Mots-clés : Biological  tissues  Cells  Molecules  3D  histoarchitecture  Tissues Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Biological tissues are ensembles of various types of cells and extracellular molecules. Functionality in tissues arises from their components (cells and extracellular molecules) as well as from the location of those components relative to each other. The organization of the constituents of a tissue is known as histoarchitecture. As cell culture reaches beyond flat, rigid surfaces, several approaches have been published that attempt to re-create in vitro the three-dimensional (3D) histoarchitecture found in vivo. In these approaches, researchers use scaffolding molecules (extracellular matrix, ECM) of natural or synthetic origin to support cell growth1. Scaffolds harvested from tissues replicate precisely the in vivo ECM but they may be limited by its biologic variability2. Conversely, synthetic scaffolds [3] and [4] provide tailored, defined, repeatable ECM but lack the chemical signaling completeness provided by biological scaffolds. Here we will review methods for replicating in vitro the 3D histoarchitecture of live tissues, focusing on those approaches that use (or are compatible with) tissue-harvested scaffolds. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700158 [article] Replication of the 3D architecture of tissues [texte imprimé] / R. Perez-Castillejos, Auteur . - 2010 . - pp. 32–41. Ingénierie Langues : Anglais (eng) in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 32–41 Mots-clés : Biological  tissues  Cells  Molecules  3D  histoarchitecture  Tissues Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Biological tissues are ensembles of various types of cells and extracellular molecules. Functionality in tissues arises from their components (cells and extracellular molecules) as well as from the location of those components relative to each other. The organization of the constituents of a tissue is known as histoarchitecture. As cell culture reaches beyond flat, rigid surfaces, several approaches have been published that attempt to re-create in vitro the three-dimensional (3D) histoarchitecture found in vivo. In these approaches, researchers use scaffolding molecules (extracellular matrix, ECM) of natural or synthetic origin to support cell growth1. Scaffolds harvested from tissues replicate precisely the in vivo ECM but they may be limited by its biologic variability2. Conversely, synthetic scaffolds [3] and [4] provide tailored, defined, repeatable ECM but lack the chemical signaling completeness provided by biological scaffolds. Here we will review methods for replicating in vitro the 3D histoarchitecture of live tissues, focusing on those approaches that use (or are compatible with) tissue-harvested scaffolds. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700158

Analysis of an ultra hard magnetic biomineral in chiton radular teeth / James C. Weaver in Materials today, Vol. 13 N° 1-2 (Janvier/Fevrier 2010) 

Public ISBD [article]  in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 42–52 Titre : Analysis of an ultra hard magnetic biomineral in chiton radular teeth Type de document : texte imprimé Auteurs : James C. Weaver, Auteur ; Qianqian Wang, Auteur ; Ali Miserez, Auteur Année de publication : 2010 Article en page(s) : pp. 42–52 Note générale : Ingénierie Langues : Anglais (eng) Mots-clés : Mineralized  biological  materials  Anisotropic  crystal  nucleation  Chiton  radular  Biominerals Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Recent analyses of the ultrastructural and mechanical properties of mineralized biological materials have demonstrated some common architectural features that can help explain their observed damage tolerance. Nature has accomplished this feat through the precise control of anisotropic crystal nucleation and growth processes in conjunction with nanoscale control over the self-assembly of spatially distinct organic and inorganic phases, resulting in effective inhibition of crack propagation through these materials. One such example is found in the hyper-mineralized and abrasion resistant radular teeth of the chitons, a group of herbivorous marine mollusks who have the surprising capacity to erode away the rocky substrates on which they graze [1], [2], [3] and [4]. Through the use of modern microscopy and nanomechanical characterization techniques, we describe the architectural and mechanical properties of the radular teeth from Cryptochiton stelleri. Chiton teeth are shown to exhibit the largest hardness and stiffness of any biominerals reported to date, being notably as much as three-fold harder than human enamel and the calcium carbonate-based shells of mollusks. We explain how the unique multi-phasic design of these materials contributes not only to their functionality, but also highlights some interesting design principles that might be applied to the fabrication of synthetic composites. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S136970211070016X [article] Analysis of an ultra hard magnetic biomineral in chiton radular teeth [texte imprimé] / James C. Weaver, Auteur ; Qianqian Wang, Auteur ; Ali Miserez, Auteur . - 2010 . - pp. 42–52. Ingénierie Langues : Anglais (eng) in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 42–52 Mots-clés : Mineralized  biological  materials  Anisotropic  crystal  nucleation  Chiton  radular  Biominerals Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Recent analyses of the ultrastructural and mechanical properties of mineralized biological materials have demonstrated some common architectural features that can help explain their observed damage tolerance. Nature has accomplished this feat through the precise control of anisotropic crystal nucleation and growth processes in conjunction with nanoscale control over the self-assembly of spatially distinct organic and inorganic phases, resulting in effective inhibition of crack propagation through these materials. One such example is found in the hyper-mineralized and abrasion resistant radular teeth of the chitons, a group of herbivorous marine mollusks who have the surprising capacity to erode away the rocky substrates on which they graze [1], [2], [3] and [4]. Through the use of modern microscopy and nanomechanical characterization techniques, we describe the architectural and mechanical properties of the radular teeth from Cryptochiton stelleri. Chiton teeth are shown to exhibit the largest hardness and stiffness of any biominerals reported to date, being notably as much as three-fold harder than human enamel and the calcium carbonate-based shells of mollusks. We explain how the unique multi-phasic design of these materials contributes not only to their functionality, but also highlights some interesting design principles that might be applied to the fabrication of synthetic composites. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S136970211070016X

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