Modeling the mechanical behavior of Lung tissue at the microlevel / Lena Wiechert in Journal of engineering mechanics, Vol. 135 N° 5 (Mai 2009)  

Public ISBD [article]  inJournal of engineering mechanics > Vol. 135 N° 5 (Mai 2009) . - pp. 434-438 Titre : Modeling the mechanical behavior of Lung tissue at the microlevel Type de document : texte imprimé Auteurs : Lena Wiechert, Auteur ; Robert Metzke, Auteur ; Wolfgang A. Wall, Auteur Article en page(s) : pp. 434-438 Note générale : Mécanique appliquée Langues : Anglais (eng) Mots-clés : Biological properties Surface dynamics Mechanical properties. Résumé : This paper is concerned with the development of a computational model of pulmonary alveoli against the background of ventilator-induced lung injuries. In order to quantify mechanical stimulation of alveolar tissue during artificial respiration, a detailed constitutive model of alveolar septa and an approach to consider interfacial phenomena is needed. For that purpose, a polyconvex hyperelastic material model formerly developed for arteries is adopted for pulmonary alveoli. Information about tissue morphology is inherently integrated into the constitutive model, therefore, establishing a connection between structure and function of the different septal constituents. Structural and interfacial dynamics are directly coupled at the alveolar surface. In order to take into account the complex behavior of surface active agents covering alveoli, a constitutive model considering dynamical changes of surface energy is employed. DEWEY : 620.1 ISSN : 0733-9399 En ligne : http://ascelibrary.aip.org/getabs/servlet/GetabsServlet?prog=normal&id=JENMDT000 [...] [article] Modeling the mechanical behavior of Lung tissue at the microlevel [texte imprimé] / Lena Wiechert, Auteur ; Robert Metzke, Auteur ; Wolfgang A. Wall, Auteur . - pp. 434-438. Mécanique appliquée Langues : Anglais (eng) in Journal of engineering mechanics > Vol. 135 N° 5 (Mai 2009) . - pp. 434-438 Mots-clés : Biological properties Surface dynamics Mechanical properties. Résumé : This paper is concerned with the development of a computational model of pulmonary alveoli against the background of ventilator-induced lung injuries. In order to quantify mechanical stimulation of alveolar tissue during artificial respiration, a detailed constitutive model of alveolar septa and an approach to consider interfacial phenomena is needed. For that purpose, a polyconvex hyperelastic material model formerly developed for arteries is adopted for pulmonary alveoli. Information about tissue morphology is inherently integrated into the constitutive model, therefore, establishing a connection between structure and function of the different septal constituents. Structural and interfacial dynamics are directly coupled at the alveolar surface. In order to take into account the complex behavior of surface active agents covering alveoli, a constitutive model considering dynamical changes of surface energy is employed. DEWEY : 620.1 ISSN : 0733-9399 En ligne : http://ascelibrary.aip.org/getabs/servlet/GetabsServlet?prog=normal&id=JENMDT000 [...]

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