Simplified finite-element model for tissue regeneration with angiogenesis / F. J. Vermolen in Journal of engineering mechanics, Vol. 135 N° 5 (Mai 2009)  

Public ISBD [article]  inJournal of engineering mechanics > Vol. 135 N° 5 (Mai 2009) . - pp. 450-460 Titre : Simplified finite-element model for tissue regeneration with angiogenesis Type de document : texte imprimé Auteurs : F. J. Vermolen, Auteur Article en page(s) : pp. 450-460 Note générale : Mécanique appliquée Langues : Anglais (eng) Mots-clés : Finite element method Mathematical models Biological properties Mechanical Human factors. Résumé : A simplified finite-element model for tissue regeneration is proposed. The model takes into account the sequential steps of angiogenesis (neo-vascularization) and wound closure (the actual healing of a wound). An innovation in the present study is the combination of both partially overlapping processes, yielding novel insights into the process of wound healing, such as geometry related influences, and could be used to investigate the influence of local injection of hormones that stimulate partial processes occurring during wound healing. These insights can be used to improve wound healing treatments. The models consist of nonlinearly coupled diffusion-reaction equations, in which transport of oxygen, growth factors, and epidermal cells and mitosis are taken into account. DEWEY : 620.1 ISSN : 0733-9399 En ligne : http://ascelibrary.aip.org/getabs/servlet/GetabsServlet?prog=normal&id=JENMDT000 [...] [article] Simplified finite-element model for tissue regeneration with angiogenesis [texte imprimé] / F. J. Vermolen, Auteur . - pp. 450-460. Mécanique appliquée Langues : Anglais (eng) in Journal of engineering mechanics > Vol. 135 N° 5 (Mai 2009) . - pp. 450-460 Mots-clés : Finite element method Mathematical models Biological properties Mechanical Human factors. Résumé : A simplified finite-element model for tissue regeneration is proposed. The model takes into account the sequential steps of angiogenesis (neo-vascularization) and wound closure (the actual healing of a wound). An innovation in the present study is the combination of both partially overlapping processes, yielding novel insights into the process of wound healing, such as geometry related influences, and could be used to investigate the influence of local injection of hormones that stimulate partial processes occurring during wound healing. These insights can be used to improve wound healing treatments. The models consist of nonlinearly coupled diffusion-reaction equations, in which transport of oxygen, growth factors, and epidermal cells and mitosis are taken into account. DEWEY : 620.1 ISSN : 0733-9399 En ligne : http://ascelibrary.aip.org/getabs/servlet/GetabsServlet?prog=normal&id=JENMDT000 [...]

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