Auteur Paul I. Barton
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Documents disponibles écrits par cet auteur (7)
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Arul Sundaramoorthy, Auteur ; James M. B. Evans, Auteur ; Paul I. Barton, Auteur |Unlike traditional batch-based pharmaceutical manufacturing, where the active pharmaceutical ingredient (API) and the final drug product are often produced in different facilities at different locations, novel continuous pharmaceutical manufactu[...]![]()
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Earl O. P. Solis, Auteur ; Paul I. Barton, Auteur ; George Stephanopoulos, Auteur |An essential requirement for the fabrication of future electronic, magnetic, optical, and biologically based devices, composed of constituents at the nanometer length scale, is the precise positioning of constituents in the system’s physical dom[...]![]()
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Earl O. P. Solis, Auteur ; Paul I. Barton, Auteur ; George Stephanopoulos, Auteur |Part 2 of this series addresses the question of how to manipulate in time the positions and intensities of external controls so that a set of self-assembling nanoscale particles can always reach the nanostructure of desired geometry, starting fr[...]![]()
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Xiang Li, Auteur ; Yang Chen, Auteur ; Paul I. Barton, Auteur |This paper considers the global optimization of challenging stochastic or multiperiod mixed-integer nonconvex programs that arise from integrated process design and operation. The difficulties of the problems are large scale and the nonconvexity[...]![]()
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Yang Chen, Auteur ; Thomas A. Adams, Auteur ; Paul I. Barton, Auteur |The optimal design and operation of flexible polygeneration systems using coal and biomass to coproduce power, liquid fuels, and chemicals is studied. In flexible systems, the various product rates change throughout the lifetime of the plant in [...]![]()
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Yang Chen, Auteur ; Thomas A. Adams, Auteur ; Paul I. Barton, Auteur |The optimal design and operation of static polygeneration systems using coal and biomass to coproduce power, liquid fuels and chemicals is studied under different economic and policy scenarios. A mathematical model including material and energy [...]![]()
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Brahim Benyahia, Auteur ; Richard Lakerveld, Auteur ; Paul I. Barton, Auteur |The pharmaceutical industry has historically benefited from high profit margins for their products, and over the years limited efforts have been made to change the main manufacturing concept from batch into continuous. However, over the past dec[...]


