| Titre : | Chemical composition, leaf trichome types and biological activities of the essential oils of four related salvia species indigenous to Southern Africa (2013) |
| Auteurs : | Guy P. P. Kamatou, Auteur ; Robyn L. Van Zyl, Auteur ; Sandy F. Van Vuuren, Auteur |
| Type de document : | Article : texte imprimé |
| Dans : | The journal of essential oil research (Vol. 18 N° Spécial, Juillet 2006) |
| Article en page(s) : | pp. 72-79 |
| Note générale : | Génie Chimique |
| Langues : | Anglais |
| Tags : | Salvia africana-caerulea africana-lutea chamelaeagnea lanceolata Lamiaceae Trichomes Biological activities Essential oil α ; -pinene Myrcene 1,8-cineole Spathulenol Caryophyllene-oxide |
| Résumé : | The essential oils from fresh aerial parts of four Salvia species indigenous to southern Africa were obtained by hydrodistillation and analyzed by GC and GC/MS. Quantitative rather than qualitative differences in oil composition were observed. Forty-three compounds in each species accounting for 78% (S. africana-caerulea), 78% (S. africana-lutea), 96% (S. chamelaeagnea) and 81% (S. lanceolata) of the total composition were identified. Salvia africana-caerulea and S. lanceolata were dominated by oxygen-containing sesquiterpenes (59% and 48%, respectively). Oxygen-containing monoterpenes dominated in S. chanuslaeagnea (43%), while monoterpene hydrocarbons (36%) were abundant in S. africana-lutea. Scanning electron and light microscopy of the indumentum of the leaves revealed the presence of glandular and non-glandular trichomes. Non-glandular point-shaped trichomes composed of two or three cells are common in all four species and two types of glandular trichomes were noted: peltate trichomes, with up to 16 head cells and a capitate type varying in the number of cells comprising the head and stalk. The oils were evaluated against two Gram-positive and two Gram-negative bacterial strains using the microdilution method and the MIC values ranged from 0.8 to 32 mg/mL. The oils exhibited antiplasmodial (5 < IC50 < 9 pg/mL) and anti-inflammatory (43 < ICc0 < 77 pg/mL) activity as determined by the [3H]-hypoxanthine radiometric and 5-lipoxygenase methods, respectively. Compared to other naturally derived antiplasmodial compounds (e.g. quinine) the oils are more toxic to human kidney epithelium cells (MTT method) with the ICc0 values ranging from 2-7 μg/mL. The oils exhibited poor antioxidant activity against the DPPH' radical at 100 pg/mL. |
| ISSN : | 1041-2905 |
| En ligne : | http://cat.inist.fr/?aModele=afficheN&cpsidt=18019087 |
