| Titre : | Fabrication of biocompatible temperature- and pH-responsive magnetic nanoparticles and their reversible agglomeration in aqueous milieu (2010) |
| Auteurs : | Liangrong Yang, Auteur ; Chen Guo, Auteur ; Lianwei Jia, Auteur |
| Type de document : | Article : texte imprimé |
| Dans : | Industrial & engineering chemistry research (Vol. 49 N° 18, Septembre 2010) |
| Article en page(s) : | pp. 8518–8525 |
| Note générale : | Industrial chemistry |
| Langues : | Anglais |
| Tags : | Nanoparticles Aqueous milieu |
| Résumé : | A novel kind of biocompatible pH- and temperature-responsive magnetic nanoparticle consisting of iron oxide nanoparticles coated with pH-responsive chitosan oligosaccharide and temperature-responsive poly(ethylene oxide)−poly(propylene oxide)−poly(ethylene oxide) block copolymer was developed. The particles were characterized by TEM, DLS, VSM, FTIR spectroscopy, and TGA. The results indicated that the self-aggregation of the prepared nanoparticles was not only caused by the thermoinduced self-assembly of the immobilized block copolymers, but also affected by the pH-induced charge property change of the particle surface. The self-assembled behaviors can be readily reversed by adjusting the pH or temperature value. Thus, the attractive properties of reversible and controllable dual-responsive self-assembly might endow the biocompatible magnetic nanoparticles with potential applications in biomedical fields such as DNA delivery, drug targeting, and tissue engineering. |
| ISSN : | 0888-5885 |
| En ligne : | http://pubs.acs.org/doi/abs/10.1021/ie100587e |
