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Absorption of carbon dioxide with ionic liquid in a rotating packed bed contactor / Liang - Liang Zhang in Industrial & engineering chemistry research, Vol. 50 N° 11 (Juin 2011) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 50 N° 11 (Juin 2011) . - pp. 6957-6964 Titre : Absorption of carbon dioxide with ionic liquid in a rotating packed bed contactor : mass transfer study Type de document : texte imprimé Auteurs : Liang - Liang Zhang, Auteur ; Jie - Xin Wang, Auteur ; Yang Xiang, Auteur Année de publication : 2011 Article en page(s) : pp. 6957-6964 Note générale : Chimie industrielle Langues : Anglais (eng) Mots-clés : Mass  transfer  Packed  bed  Ionic  liquid  Carbon  dioxide Résumé : Using ionic liquids for CO2 capture is of great interest due to their unique characteristics. However, low gas―liquid mass transfer rates in conventional gas-liquid contactors due to the high viscosities of ionic liquids lead to the significant limitation for large-scale applications of CO2 capture using ionic liquids. Therefore, there is an urgent demand to develop a novel gas―liquid contactor for the intensification of the mass transfer efficiency in such a system. In this article, CO2 absorption with an ionic liquid in a rotating packed bed (RPB) gas-liquid contactor is first reported. It was found that the RPB markedly enhanced the physical absorption of CO2 in the ionic liquid in a very short contact time, within seconds. Only one cycle gas-liquid contact in the RPB could make the saturation ratio of CO2 in the ionic liquid reach 60%. The effects of various operation conditions on the liquid side volumetric mass transfer coefficient (kLα) were elucidated. Increasing the rotating speed from 1100 to 3100 rpm doubled the kLα. The increase of the liquid flow rate also benefited the enhancement of the kLα. The experimentally measured kLα in the RPB is at least 1 order of magnitude higher than that in a conventional packed tower. A model based on penetration theory was proposed to describe the mechanism of gas―liquid mass transfer in the RPB. The predicted kLα was in good agreement with the experimental data with a deviation of less than 15%. The RPB shows great potential for the industrial application of CO2 capture using ionic liquids. DEWEY : 660 ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=24199914 [article] Absorption of carbon dioxide with ionic liquid in a rotating packed bed contactor : mass transfer study [texte imprimé] / Liang - Liang Zhang, Auteur ; Jie - Xin Wang, Auteur ; Yang Xiang, Auteur . - 2011 . - pp. 6957-6964. Chimie industrielle Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 50 N° 11 (Juin 2011) . - pp. 6957-6964 Mots-clés : Mass  transfer  Packed  bed  Ionic  liquid  Carbon  dioxide Résumé : Using ionic liquids for CO2 capture is of great interest due to their unique characteristics. However, low gas―liquid mass transfer rates in conventional gas-liquid contactors due to the high viscosities of ionic liquids lead to the significant limitation for large-scale applications of CO2 capture using ionic liquids. Therefore, there is an urgent demand to develop a novel gas―liquid contactor for the intensification of the mass transfer efficiency in such a system. In this article, CO2 absorption with an ionic liquid in a rotating packed bed (RPB) gas-liquid contactor is first reported. It was found that the RPB markedly enhanced the physical absorption of CO2 in the ionic liquid in a very short contact time, within seconds. Only one cycle gas-liquid contact in the RPB could make the saturation ratio of CO2 in the ionic liquid reach 60%. The effects of various operation conditions on the liquid side volumetric mass transfer coefficient (kLα) were elucidated. Increasing the rotating speed from 1100 to 3100 rpm doubled the kLα. The increase of the liquid flow rate also benefited the enhancement of the kLα. The experimentally measured kLα in the RPB is at least 1 order of magnitude higher than that in a conventional packed tower. A model based on penetration theory was proposed to describe the mechanism of gas―liquid mass transfer in the RPB. The predicted kLα was in good agreement with the experimental data with a deviation of less than 15%. The RPB shows great potential for the industrial application of CO2 capture using ionic liquids. DEWEY : 660 ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=24199914

High throughput methodology for continuous preparation of hydroxyapatite nanoparticles in a microporous tube-in-tube microchannel reactor / Qing Yang in Industrial & engineering chemistry research, Vol. 49 N° 1 (Janvier 2010) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 49 N° 1 (Janvier 2010) . - pp. 140–147 Titre : High throughput methodology for continuous preparation of hydroxyapatite nanoparticles in a microporous tube-in-tube microchannel reactor Type de document : texte imprimé Auteurs : Qing Yang, Auteur ; Jie - Xin Wang, Auteur ; Lei Shao, Auteur Année de publication : 2010 Article en page(s) : pp. 140–147 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Throughput--Methodology--Continuous--Hydroxyapatite--Nanoparticles--Microporous--Tube-in-Tube--Microchannel  Reactor Résumé : A microporous tube-in-tube microchannel reactor (MTMCR) was successfully adopted to prepare hydroxyapatite (HAP) nanoparticles. The rodlike HAP nanoparticles with a mean size of 58 nm, a specific surface area of 49.32 m2/g, and a narrow size distribution were obtained in an MTMCR under a high throughput of 3 L/min. The mean particle size sharply decreased with increasing the continuous phase flow rate, while first decreased and subsequently increased with increasing the dispersed phase flow rate and the reactant concentration. The extension of the mixing distance led to the initial rapid and following slight decrease of the mean particle size. The size of HAP nanoparticles was also strongly dependent on the micropore size on the surface of inner tube. Small micropore size was beneficial for producing small particles. For comparison, HAP nanoparticles were also prepared in a stirred tank reactor (STR) and a T-junction microchannel reactor (TMCR), clearly exhibiting the advantages of the MTMCR over the STR and TMCR due to the achievement of uniformly smaller HAP nanoparticles and a high throughput for industrial production. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie9005436 [article] High throughput methodology for continuous preparation of hydroxyapatite nanoparticles in a microporous tube-in-tube microchannel reactor [texte imprimé] / Qing Yang, Auteur ; Jie - Xin Wang, Auteur ; Lei Shao, Auteur . - 2010 . - pp. 140–147. Industrial chemistry Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 49 N° 1 (Janvier 2010) . - pp. 140–147 Mots-clés : Throughput--Methodology--Continuous--Hydroxyapatite--Nanoparticles--Microporous--Tube-in-Tube--Microchannel  Reactor Résumé : A microporous tube-in-tube microchannel reactor (MTMCR) was successfully adopted to prepare hydroxyapatite (HAP) nanoparticles. The rodlike HAP nanoparticles with a mean size of 58 nm, a specific surface area of 49.32 m2/g, and a narrow size distribution were obtained in an MTMCR under a high throughput of 3 L/min. The mean particle size sharply decreased with increasing the continuous phase flow rate, while first decreased and subsequently increased with increasing the dispersed phase flow rate and the reactant concentration. The extension of the mixing distance led to the initial rapid and following slight decrease of the mean particle size. The size of HAP nanoparticles was also strongly dependent on the micropore size on the surface of inner tube. Small micropore size was beneficial for producing small particles. For comparison, HAP nanoparticles were also prepared in a stirred tank reactor (STR) and a T-junction microchannel reactor (TMCR), clearly exhibiting the advantages of the MTMCR over the STR and TMCR due to the achievement of uniformly smaller HAP nanoparticles and a high throughput for industrial production. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie9005436

Investigation of micromixing efficiency in a novel high-throughput microporous tube-in-tube microchannel reactor / Qi-An Wang in Industrial & engineering chemistry research, Vol. 48 N° 10 (Mai 2009) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 48 N° 10 (Mai 2009) . - pp. 5004–5009 Titre : Investigation of micromixing efficiency in a novel high-throughput microporous tube-in-tube microchannel reactor Type de document : texte imprimé Auteurs : Qi-An Wang, Auteur ; Jie - Xin Wang, Auteur ; Wen Yu, Auteur Année de publication : 2009 Article en page(s) : pp. 5004–5009 Note générale : Chemical engineering Langues : Anglais (eng) Mots-clés : Microporous  tube-in-tube  microchannel  reactor  Throughput  Micromixing  performance Résumé : This article presents a new microporous tube-in-tube microchannel reactor (MTMCR) with high throughput and excellent micromixing performance. In the MTMCR, one liquid from the inner tube is divided into many liquid fragments through the microscale pores in the walls, and then these fragments vertically collide with another flowing annular liquid sheet between the inner and outer tubes, generating cross-flow. The annular microchannel allows a mass of fluid to go through it rapidly without enlarging the channel width, thereby achieving a throughput as high as 9 L/min (typical microreactor throughput = 4−100 mL/min). Furthermore, the micromixing performance is expressed in terms of a segregation index, which can be as low as 0.0007. The micromixing time evaluated by the incorporation model reaches the magnitude of milliseconds. In addition, several factors affecting the micromixing such as reactant concentration, flow rate, volume flow ratio, micropore size, and channel width were investigated. The results indicated that an increase of the flow rate, as well as a reduction of the micropore size and channel width, could greatly intensify the micromixing. Therefore, it can be envisioned that the MTMCR would exhibit great potential for various industrial applications in the future. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie801424r [article] Investigation of micromixing efficiency in a novel high-throughput microporous tube-in-tube microchannel reactor [texte imprimé] / Qi-An Wang, Auteur ; Jie - Xin Wang, Auteur ; Wen Yu, Auteur . - 2009 . - pp. 5004–5009. Chemical engineering Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 48 N° 10 (Mai 2009) . - pp. 5004–5009 Mots-clés : Microporous  tube-in-tube  microchannel  reactor  Throughput  Micromixing  performance Résumé : This article presents a new microporous tube-in-tube microchannel reactor (MTMCR) with high throughput and excellent micromixing performance. In the MTMCR, one liquid from the inner tube is divided into many liquid fragments through the microscale pores in the walls, and then these fragments vertically collide with another flowing annular liquid sheet between the inner and outer tubes, generating cross-flow. The annular microchannel allows a mass of fluid to go through it rapidly without enlarging the channel width, thereby achieving a throughput as high as 9 L/min (typical microreactor throughput = 4−100 mL/min). Furthermore, the micromixing performance is expressed in terms of a segregation index, which can be as low as 0.0007. The micromixing time evaluated by the incorporation model reaches the magnitude of milliseconds. In addition, several factors affecting the micromixing such as reactant concentration, flow rate, volume flow ratio, micropore size, and channel width were investigated. The results indicated that an increase of the flow rate, as well as a reduction of the micropore size and channel width, could greatly intensify the micromixing. Therefore, it can be envisioned that the MTMCR would exhibit great potential for various industrial applications in the future. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie801424r

Microfluidic fabrication of monodispersed pharmaceutical colloidal spheres of atorvastatin calcium with tunable sizes / Hai-Xia Zhang in Industrial & engineering chemistry research, Vol. 49 N° 9 (Mai 2010) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 49 N° 9 (Mai 2010) . - pp. 4156–4161 Titre : Microfluidic fabrication of monodispersed pharmaceutical colloidal spheres of atorvastatin calcium with tunable sizes Type de document : texte imprimé Auteurs : Hai-Xia Zhang, Auteur ; Jie - Xin Wang, Auteur ; Lei Shao, Auteur Année de publication : 2010 Article en page(s) : pp. 4156–4161 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Microfluidic Résumé : In this work, monodispersed pharmaceutical colloidal spheres of atorvastatin calcium (AC) with tunable sizes have been synthesized in a microfluidic system at continuous flow conditions. The influences of the key parameters, including the concentration of the AC methanol solution, the overall flow rate, the flow rate of isopropanol, and the flow rate of the AC methanol solution on particle size and size distribution were discussed. The results indicated that the drug concentration and the flow rate could efficiently control the particle size and improve the polydispersity of the resulting particles. The particle size decreased from 760 to 300 nm with an increase in the AC concentration from 30 to 60 mg/mL and significantly increased from 430 to 2500 nm with an increase in the flow rate of the AC methanol solution from 2.7 to 16 mL/min. However, with the increase of the overall flow rate at a fixed flow ratio of 10, the particle size slightly decreased from 240 (10/1 mL/min) to 210 nm (30/3 mL/min) and then dramatically increased to 680 nm (80/8 mL/min). Also, the particle size first decreased and then increased with an increase in the flow rate of isopropanol. The prepared AC colloidal spheres were amorphous and displayed enhanced dissolution rate compared with the commercial AC. This work shows that the continuous synthesis in a microfluidic reactor is a simple and economic way to prepare monodispersed pharmaceutical colloidal particles or nanoparticles with tunable sizes. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie901365w [article] Microfluidic fabrication of monodispersed pharmaceutical colloidal spheres of atorvastatin calcium with tunable sizes [texte imprimé] / Hai-Xia Zhang, Auteur ; Jie - Xin Wang, Auteur ; Lei Shao, Auteur . - 2010 . - pp. 4156–4161. Industrial chemistry Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 49 N° 9 (Mai 2010) . - pp. 4156–4161 Mots-clés : Microfluidic Résumé : In this work, monodispersed pharmaceutical colloidal spheres of atorvastatin calcium (AC) with tunable sizes have been synthesized in a microfluidic system at continuous flow conditions. The influences of the key parameters, including the concentration of the AC methanol solution, the overall flow rate, the flow rate of isopropanol, and the flow rate of the AC methanol solution on particle size and size distribution were discussed. The results indicated that the drug concentration and the flow rate could efficiently control the particle size and improve the polydispersity of the resulting particles. The particle size decreased from 760 to 300 nm with an increase in the AC concentration from 30 to 60 mg/mL and significantly increased from 430 to 2500 nm with an increase in the flow rate of the AC methanol solution from 2.7 to 16 mL/min. However, with the increase of the overall flow rate at a fixed flow ratio of 10, the particle size slightly decreased from 240 (10/1 mL/min) to 210 nm (30/3 mL/min) and then dramatically increased to 680 nm (80/8 mL/min). Also, the particle size first decreased and then increased with an increase in the flow rate of isopropanol. The prepared AC colloidal spheres were amorphous and displayed enhanced dissolution rate compared with the commercial AC. This work shows that the continuous synthesis in a microfluidic reactor is a simple and economic way to prepare monodispersed pharmaceutical colloidal particles or nanoparticles with tunable sizes. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie901365w

Nanonization of megestrol acetate by liquid precipitation / Zhi-Bing Zhang in Industrial & engineering chemistry research, Vol. 48 N° 18 (Septembre 2009) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 48 N° 18 (Septembre 2009) . - pp. 8493–8499 Titre : Nanonization of megestrol acetate by liquid precipitation Type de document : texte imprimé Auteurs : Zhi-Bing Zhang, Auteur ; Zhi-Gang Shen, Auteur ; Jie - Xin Wang, Auteur Année de publication : 2010 Article en page(s) : pp. 8493–8499 Note générale : Chemical engineering Langues : Anglais (eng) Mots-clés : Megestrol  acetate  nanoparticles  Liquid  precipitation  technique Résumé : The purpose of this study was to prepare megestrol acetate (MA) nanoparticles via a liquid precipitation technique. Several experimental parameters, such as the stabilizer combination, the volume ratio of antisolvent to drug solution, the temperature, the stirring speed, and the drying method were investigated. The as-prepared MA particles had a mean size of 208 nm, and 90% of the particles were distributed in the range of 100−300 nm, whereas the raw MA had a mean particle size of about 3.02 μm, ranging widely from 0.2 μm to 30 μm. X-ray diffraction (XRD), differential scanning calorimetry (DSC), and Fourier transform infrared (FTIR) analysis indicated that MA nanoparticles exhibited decreased crystallinity and unchanged chemical group structure after precipitation. The freeze-dried MA nanoparticles exhibited improved wettability as demonstrated by the contact angle measurement result proving that particles were covered by a hydrophilic layer. In dissolution rate tests, the nanoparticles achieved 100% drug dissolution within 5 min, while the raw MA did not dissolve completely after 120 min, suggesting that the dissolution property of MA nanoparticles was significantly enhanced. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie900944y [article] Nanonization of megestrol acetate by liquid precipitation [texte imprimé] / Zhi-Bing Zhang, Auteur ; Zhi-Gang Shen, Auteur ; Jie - Xin Wang, Auteur . - 2010 . - pp. 8493–8499. Chemical engineering Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 48 N° 18 (Septembre 2009) . - pp. 8493–8499 Mots-clés : Megestrol  acetate  nanoparticles  Liquid  precipitation  technique Résumé : The purpose of this study was to prepare megestrol acetate (MA) nanoparticles via a liquid precipitation technique. Several experimental parameters, such as the stabilizer combination, the volume ratio of antisolvent to drug solution, the temperature, the stirring speed, and the drying method were investigated. The as-prepared MA particles had a mean size of 208 nm, and 90% of the particles were distributed in the range of 100−300 nm, whereas the raw MA had a mean particle size of about 3.02 μm, ranging widely from 0.2 μm to 30 μm. X-ray diffraction (XRD), differential scanning calorimetry (DSC), and Fourier transform infrared (FTIR) analysis indicated that MA nanoparticles exhibited decreased crystallinity and unchanged chemical group structure after precipitation. The freeze-dried MA nanoparticles exhibited improved wettability as demonstrated by the contact angle measurement result proving that particles were covered by a hydrophilic layer. In dissolution rate tests, the nanoparticles achieved 100% drug dissolution within 5 min, while the raw MA did not dissolve completely after 120 min, suggesting that the dissolution property of MA nanoparticles was significantly enhanced. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie900944y

Preparation of hydroxyaptite nanoparticles by using high - gravity reactive precipitation combined with hydrothermal method / Qing Yang in Industrial & engineering chemistry research, Vol. 49 N° 20 (Octobre 2010) 

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