Auteur Arul Sundaramoorthy
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Documents disponibles écrits par cet auteur (5)
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Arul Sundaramoorthy, Auteur ; James M. B. Evans, Auteur ; Paul I. Barton, Auteur |Unlike traditional batch-based pharmaceutical manufacturing, where the active pharmaceutical ingredient (API) and the final drug product are often produced in different facilities at different locations, novel continuous pharmaceutical manufactu[...]![]()
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Arul Sundaramoorthy, Auteur ; Xiang Li, Auteur ; James M. B. Evans, Auteur |In Part 1 of this paper, we presented a scenario-based multiperiod mixed-integer linear programming (MILP) formulation for a capacity planning problem in continuous pharmaceutical manufacturing under clinical trials uncertainty. The number of sc[...]![]()
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Arul Sundaramoorthy, Auteur ; Christos T. Maravelias, Auteur |The goal of this paper is to discuss the modeling aspects and study the computational performance of scheduling approaches for batch process networks that are based on discrete-time and continuous-time representations. First, we compare the abov[...]![]()
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Arul Sundaramoorthy, Auteur ; Christos T. Maravelias, Auteur |The goal of this paper is the development of a mixed-integer programming formulation for the simultaneous batching and scheduling in multiproduct multistage processes with storage constraints. Storage vessels are modeled as additional proces[...]![]()
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Arul Sundaramoorthy, Auteur ; Christos T. Maravelias, Auteur ; Pradeep Prasad, Auteur |We present a novel discrete-time mixed-integer programming (MIP) formulation for the simultaneous batching and scheduling in multiproduct multistage processes under utility constraints. In addition to processing units and storage vessels, we con[...]


