Article : texte imprimé

A Spatial branch-and-bound framework for the global optimization of kinetic models of metabolic networks

C. Pozo, Auteur ; Gonzalo Guillen-Gosalbez, Auteur ; A. Sorribas, Auteur |

Dans Industrial & engineering chemistry research (Vol. 50 N° 9, Mai 2011)

The identification of the enzymatic profile that achieves a maximal production rate of a given metabolite is an important problem in the biotechnological industry, especially if there is a limit on the number of enzymatic modulations allowed. Th[...]

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