| Titre : | Use of calorimetry model and batch control technique for scale-up of unseeded batch cooling crystallization of poly(hydroxybenzophenone) (2009) |
| Auteurs : | Huiyong Kim, Auteur ; Yookyung Bang, Auteur ; Kwang Soon Lee, Auteur |
| Type de document : | Article : texte imprimé |
| Dans : | Industrial & engineering chemistry research (Vol. 48 N° 14, Juillet 2009) |
| Article en page(s) : | pp. 6776–6782 |
| Note générale : | Chemical engineering |
| Langues : | Anglais |
| Tags : | Scale-up method Cooling crystallization Poly(hydroxybenzophenone) Crystallization |
| Résumé : | A scale-up method to design and implement a cooling profile for unseeded batch cooling crystallization has been investigated. The reduced ratio between the heat-transfer area and the volume during scale-up to a large crystallizer causes an increase in the temperature distribution in the reactor, which can trigger unwanted nucleation around the cold spots of the vessel wall. To address this problem, a method is proposed to design a cooling profile for a scaled-up crystallizer that can replicate the seed-generation stage of a small crystallizer by effectively suppressing the unwanted nucleation. The use of a batch control technique as method of implementing the cooling profile in a large crystallizer is also proposed. Experiments were conducted with a 100 mL reactor and a 5 L scaled-up reactor for the unseeded crystallization of poly(hydroxybenzophenone) (PHBP) to verify the performance of the proposed method. |
| En ligne : | http://pubs.acs.org/doi/abs/10.1021/ie801039f |
