Documents disponibles écrits par cet auteur

Effect of supersaturation on the morphology of coated surface in coating by solution crystallization / Jae-Wook Jung in Industrial & engineering chemistry research, Vol. 50 N° 6 (Mars 2011) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 50 N° 6 (Mars 2011) . - pp. 3475-3482 Titre : Effect of supersaturation on the morphology of coated surface in coating by solution crystallization Type de document : texte imprimé Auteurs : Jae-Wook Jung, Auteur ; Kwang-Joo Kim, Auteur Année de publication : 2011 Article en page(s) : pp. 3475-3482 Note générale : Chimie industrielle Langues : Anglais (eng) Mots-clés : Solution  crystallization  Morphology  Supersaturation Résumé : HMX (cyclotetramethylene tetranitramine) was coated with NTO (3-nitro-1,2,4-triazole-5-one) by solution crystallization. Two-step coating crystallization was investigated to enhance coating morphology. The first coating process using HMX seed and the second coating process using HMX coated with NTO obtained from the first process were compared in terms of coating shape, coating surface, nucleation rate, metastable zone width, and interfacial energy. The objective of this study was to examine how operating conditions affected the surface morphology by coating crystallization. The parameters such as type of seed, concentration, and cooling rate were used in the crystallization process. Finally, the second coating process was found to achieve compact and uniform surfaces of NTO crystals coated on the HMX surface. It was found that higher supersaturation enhances cluster aggregation, which results in uniform coating on the HMX surface. DEWEY : 660 ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=23944514 [article] Effect of supersaturation on the morphology of coated surface in coating by solution crystallization [texte imprimé] / Jae-Wook Jung, Auteur ; Kwang-Joo Kim, Auteur . - 2011 . - pp. 3475-3482. Chimie industrielle Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 50 N° 6 (Mars 2011) . - pp. 3475-3482 Mots-clés : Solution  crystallization  Morphology  Supersaturation Résumé : HMX (cyclotetramethylene tetranitramine) was coated with NTO (3-nitro-1,2,4-triazole-5-one) by solution crystallization. Two-step coating crystallization was investigated to enhance coating morphology. The first coating process using HMX seed and the second coating process using HMX coated with NTO obtained from the first process were compared in terms of coating shape, coating surface, nucleation rate, metastable zone width, and interfacial energy. The objective of this study was to examine how operating conditions affected the surface morphology by coating crystallization. The parameters such as type of seed, concentration, and cooling rate were used in the crystallization process. Finally, the second coating process was found to achieve compact and uniform surfaces of NTO crystals coated on the HMX surface. It was found that higher supersaturation enhances cluster aggregation, which results in uniform coating on the HMX surface. DEWEY : 660 ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=23944514

Quantitative study on polymorphic form in solution crystallization of clopidogrel hydrogen sulfate / Hye-Jin Kim in Industrial & engineering chemistry research, Vol. 48 N° 24 (Décembre 2009) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 48 N° 24 (Décembre 2009) . - pp. 11133–11139 Titre : Quantitative study on polymorphic form in solution crystallization of clopidogrel hydrogen sulfate Type de document : texte imprimé Auteurs : Hye-Jin Kim, Auteur ; Kwang-Joo Kim, Auteur Année de publication : 2010 Article en page(s) : pp. 11133–11139 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Quantitative--Study--Polymorphic--Solution--Crystallization--Clopidogrel--Hydrogen--Sulfate Résumé : The concentration of polymorphs was explored by the ultrasonic measuring technique during crystallization in solution. The polymorphic form of the crystallized solid, the concentration of the solution, and the transformation of polymorphs were found by the ultrasonic measuring technique. The ultrasonic velocity calibrated at known solid and liquid concentrations has been applied to determine quantitatively the polymorphic compositions for various process conditions. Additionally, it can be used to estimate the solute concentration and the supersaturation of solution during the transformation of polymorphs. Multivariate data analysis from the ultrasonic measuring technique was used to determine the kinetics of polymorph transformation and to simulate the transformation process. It was found that the transformation of polymorphs occurred simultaneously with crystallization of a polymorph in the solution. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie900715w [article] Quantitative study on polymorphic form in solution crystallization of clopidogrel hydrogen sulfate [texte imprimé] / Hye-Jin Kim, Auteur ; Kwang-Joo Kim, Auteur . - 2010 . - pp. 11133–11139. Industrial chemistry Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 48 N° 24 (Décembre 2009) . - pp. 11133–11139 Mots-clés : Quantitative--Study--Polymorphic--Solution--Crystallization--Clopidogrel--Hydrogen--Sulfate Résumé : The concentration of polymorphs was explored by the ultrasonic measuring technique during crystallization in solution. The polymorphic form of the crystallized solid, the concentration of the solution, and the transformation of polymorphs were found by the ultrasonic measuring technique. The ultrasonic velocity calibrated at known solid and liquid concentrations has been applied to determine quantitatively the polymorphic compositions for various process conditions. Additionally, it can be used to estimate the solute concentration and the supersaturation of solution during the transformation of polymorphs. Multivariate data analysis from the ultrasonic measuring technique was used to determine the kinetics of polymorph transformation and to simulate the transformation process. It was found that the transformation of polymorphs occurred simultaneously with crystallization of a polymorph in the solution. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie900715w

Quantitative study on polymorphic form in solution crystallization of clopidogrel hydrogen sulfate / Hye-Jin Kim in Industrial & engineering chemistry research, Vol. 48 N° 24 (Décembre 2009) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 48 N° 24 (Décembre 2009) . - pp. 11133–11139 Titre : Quantitative study on polymorphic form in solution crystallization of clopidogrel hydrogen sulfate Type de document : texte imprimé Auteurs : Hye-Jin Kim, Auteur ; Kwang-Joo Kim, Auteur Année de publication : 2010 Article en page(s) : pp. 11133–11139 Note générale : Chemical engineering Langues : Anglais (eng) Mots-clés : Polymorphs  Crystallized  solid  Ultrasonic  velocity Résumé : The concentration of polymorphs was explored by the ultrasonic measuring technique during crystallization in solution. The polymorphic form of the crystallized solid, the concentration of the solution, and the transformation of polymorphs were found by the ultrasonic measuring technique. The ultrasonic velocity calibrated at known solid and liquid concentrations has been applied to determine quantitatively the polymorphic compositions for various process conditions. Additionally, it can be used to estimate the solute concentration and the supersaturation of solution during the transformation of polymorphs. Multivariate data analysis from the ultrasonic measuring technique was used to determine the kinetics of polymorph transformation and to simulate the transformation process. It was found that the transformation of polymorphs occurred simultaneously with crystallization of a polymorph in the solution. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie900715w [article] Quantitative study on polymorphic form in solution crystallization of clopidogrel hydrogen sulfate [texte imprimé] / Hye-Jin Kim, Auteur ; Kwang-Joo Kim, Auteur . - 2010 . - pp. 11133–11139. Chemical engineering Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 48 N° 24 (Décembre 2009) . - pp. 11133–11139 Mots-clés : Polymorphs  Crystallized  solid  Ultrasonic  velocity Résumé : The concentration of polymorphs was explored by the ultrasonic measuring technique during crystallization in solution. The polymorphic form of the crystallized solid, the concentration of the solution, and the transformation of polymorphs were found by the ultrasonic measuring technique. The ultrasonic velocity calibrated at known solid and liquid concentrations has been applied to determine quantitatively the polymorphic compositions for various process conditions. Additionally, it can be used to estimate the solute concentration and the supersaturation of solution during the transformation of polymorphs. Multivariate data analysis from the ultrasonic measuring technique was used to determine the kinetics of polymorph transformation and to simulate the transformation process. It was found that the transformation of polymorphs occurred simultaneously with crystallization of a polymorph in the solution. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie900715w

Transformation of monohydrate into anhydrous form of risedronate monosodium in methanol − water mixture / Thi Nhat Phuong Nguyen in Industrial & engineering chemistry research, Vol. 49 N° 10 (Mai 2010) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 49 N° 10 (Mai 2010) . - pp. 4842–4849 Titre : Transformation of monohydrate into anhydrous form of risedronate monosodium in methanol − water mixture Type de document : texte imprimé Auteurs : Thi Nhat Phuong Nguyen, Auteur ; Kwang-Joo Kim, Auteur Année de publication : 2010 Article en page(s) : pp. 4842–4849 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Monohydrate  Methanol Résumé : The transformation of a monohydrate into an anhydrous form of risedronate monosodium (RS) in a methanol and water mixture was investigated. The phase transformation was detected by monitoring the number of particles, particle size, and shape. At the same time, polymorphic forms of crystals were identified by various offline techniques such as XRPD, TGA, and DSC. The kinetics of phase transformation was found to be controlled by three-dimensional nuclear growth. The reaction of water in the solvent mixture was a main factor determining the stability of anhydrate and monohydrate forms. The time required for phase transformation was strongly affected by temperature and agitation rate. The phase transformation could be successfully determined in real time by using an in situ particle measurement system. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie901677n [article] Transformation of monohydrate into anhydrous form of risedronate monosodium in methanol − water mixture [texte imprimé] / Thi Nhat Phuong Nguyen, Auteur ; Kwang-Joo Kim, Auteur . - 2010 . - pp. 4842–4849. Industrial chemistry Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 49 N° 10 (Mai 2010) . - pp. 4842–4849 Mots-clés : Monohydrate  Methanol Résumé : The transformation of a monohydrate into an anhydrous form of risedronate monosodium (RS) in a methanol and water mixture was investigated. The phase transformation was detected by monitoring the number of particles, particle size, and shape. At the same time, polymorphic forms of crystals were identified by various offline techniques such as XRPD, TGA, and DSC. The kinetics of phase transformation was found to be controlled by three-dimensional nuclear growth. The reaction of water in the solvent mixture was a main factor determining the stability of anhydrate and monohydrate forms. The time required for phase transformation was strongly affected by temperature and agitation rate. The phase transformation could be successfully determined in real time by using an in situ particle measurement system. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie901677n