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Antimicrobial activity of the essential oils from the leaves of two morphotypes of Croton cajucara Benth / Mariana M. B. Azevedo in The journal of essential oil research, Vol. 24 N° 4 (Août 2012) 

Public ISBD [article]  in The journal of essential oil research > Vol. 24 N° 4 (Août 2012) . - pp. 351-357 Titre : Antimicrobial activity of the essential oils from the leaves of two morphotypes of Croton cajucara Benth Type de document : texte imprimé Auteurs : Mariana M. B. Azevedo, Auteur ; Aline Q. Pereira, Auteur ; Francisco C. M. Chaves, Auteur Année de publication : 2012 Article en page(s) : pp. 351-357 Note générale : Génie Chimique Langues : Anglais (eng) Mots-clés : Antimicrobial  activity  Essential  oil  composition  Croton  cajucara  Candida  albicans  Staphylococcus  aureus  Linalool  7-hydroxycalamenene Résumé : Croton cajucara Benth. (Euphorbiaceae) is a shrub native to Amazon region and locally known as sacaca. Two morphotypes are known, namely white ‘sacaca’ and red ‘sacaca’. The essential oils from the leaves of these morphotypes are rich in linalool and 7-hydroxycalamenene, respectively. The effectiveness of the oils from forty individuals from a germplasm bank regarding the antimicrobial activity against Staphylococcus aureus and Candida albicans was investigated by drop diffusion (or agar diffusion) method. Expressive inhibition zones for both microorganisms tested were observed. Essential oils rich in 7-hydroxycalamenene were more effective against S. aureus while linalool-rich essential oils acted inhibiting C. albicans. The minimal inhibitory (MIC) and microbicidal concentrations of the main constituents of the oils were also determined, using broth dilution assay. It was observed that isolated 7-hydroxycalamenene presented high bactericidal activity, with a MIC of 0.3 μg/mL, while for fungicidal activity a MIC of 45 μg/mL was recorded. For S. aureus, the isolated 7-hydroxycalamenene was more active than the whole oil, whereas the linalool-rich essential oil presented higher bactericide activity than pure linalool. For C. albicans, however, pure linalool was more active than the whole essential oil. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/full/10.1080/10412905.2012.692902 [article] Antimicrobial activity of the essential oils from the leaves of two morphotypes of Croton cajucara Benth [texte imprimé] / Mariana M. B. Azevedo, Auteur ; Aline Q. Pereira, Auteur ; Francisco C. M. Chaves, Auteur . - 2012 . - pp. 351-357. Génie Chimique Langues : Anglais (eng) in The journal of essential oil research > Vol. 24 N° 4 (Août 2012) . - pp. 351-357 Mots-clés : Antimicrobial  activity  Essential  oil  composition  Croton  cajucara  Candida  albicans  Staphylococcus  aureus  Linalool  7-hydroxycalamenene Résumé : Croton cajucara Benth. (Euphorbiaceae) is a shrub native to Amazon region and locally known as sacaca. Two morphotypes are known, namely white ‘sacaca’ and red ‘sacaca’. The essential oils from the leaves of these morphotypes are rich in linalool and 7-hydroxycalamenene, respectively. The effectiveness of the oils from forty individuals from a germplasm bank regarding the antimicrobial activity against Staphylococcus aureus and Candida albicans was investigated by drop diffusion (or agar diffusion) method. Expressive inhibition zones for both microorganisms tested were observed. Essential oils rich in 7-hydroxycalamenene were more effective against S. aureus while linalool-rich essential oils acted inhibiting C. albicans. The minimal inhibitory (MIC) and microbicidal concentrations of the main constituents of the oils were also determined, using broth dilution assay. It was observed that isolated 7-hydroxycalamenene presented high bactericidal activity, with a MIC of 0.3 μg/mL, while for fungicidal activity a MIC of 45 μg/mL was recorded. For S. aureus, the isolated 7-hydroxycalamenene was more active than the whole oil, whereas the linalool-rich essential oil presented higher bactericide activity than pure linalool. For C. albicans, however, pure linalool was more active than the whole essential oil. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/full/10.1080/10412905.2012.692902

Isolation and identification of cis-7- hydroxycalamenene from the essential oil of croton cajucara benth. / Aline Q. Pereira in The journal of essential oil research, Vol. 23 N° 2 (Mars/Avril 2011) 

Public ISBD [article]  in The journal of essential oil research > Vol. 23 N° 2 (Mars/Avril 2011) . - pp. 20-23 Titre : Isolation and identification of cis-7- hydroxycalamenene from the essential oil of croton cajucara benth. Type de document : texte imprimé Auteurs : Aline Q. Pereira, Auteur ; Francisco C. M. Chaves, Auteur ; Shaft C. Pinto, Auteur Année de publication : 2011 Article en page(s) : pp. 20-23 Note générale : Génie Chimique Langues : Anglais (eng) Mots-clés : Croton  cajucara  Euphorbiaceae  Essential  oil  composition  Cis-7-hydroxycalamenene  Linalool  Linear  retention  indices Index. décimale : 646 Résumé : During agronomical and chemical studies with Croton cajucara Benth. (Euphorbiaceae), a shrub native to the Amazon area possessing an essential oil rich in linalool, it was observed that some individuals of a germplasm bank produced an oil containing a hydroxylated sesquiterpene as major component (up to 44.3%). Originally misidentified as 5-hydroxycalamenene, the compound was further isolated and properly identified by 1H and 13C NMR as cis-7-hydroxycalamenene. Measured retention indices were 1759 (Ultra-1), 1804 (HP-5), 2212 (FFAP) and 2663 (Carbowax 20M). DEWEY : 665 ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/abs/10.1080/10412905.2011.9700442 [article] Isolation and identification of cis-7- hydroxycalamenene from the essential oil of croton cajucara benth. [texte imprimé] / Aline Q. Pereira, Auteur ; Francisco C. M. Chaves, Auteur ; Shaft C. Pinto, Auteur . - 2011 . - pp. 20-23. Génie Chimique Langues : Anglais (eng) in The journal of essential oil research > Vol. 23 N° 2 (Mars/Avril 2011) . - pp. 20-23 Mots-clés : Croton  cajucara  Euphorbiaceae  Essential  oil  composition  Cis-7-hydroxycalamenene  Linalool  Linear  retention  indices Index. décimale : 646 Résumé : During agronomical and chemical studies with Croton cajucara Benth. (Euphorbiaceae), a shrub native to the Amazon area possessing an essential oil rich in linalool, it was observed that some individuals of a germplasm bank produced an oil containing a hydroxylated sesquiterpene as major component (up to 44.3%). Originally misidentified as 5-hydroxycalamenene, the compound was further isolated and properly identified by 1H and 13C NMR as cis-7-hydroxycalamenene. Measured retention indices were 1759 (Ultra-1), 1804 (HP-5), 2212 (FFAP) and 2663 (Carbowax 20M). DEWEY : 665 ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/abs/10.1080/10412905.2011.9700442