Documents disponibles écrits par cet auteur

Advanced control strategies for the regulation of hypnosis with propofol / Yelneedi Sreenivas in Industrial & engineering chemistry research, Vol. 48 N° 8 (Avril 2009) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 48 N° 8 (Avril 2009) . - pp. 3880–3897 Titre : Advanced control strategies for the regulation of hypnosis with propofol Type de document : texte imprimé Auteurs : Yelneedi Sreenivas, Auteur ; Lakshminarayanan Samavedham, Auteur ; G.P. Rangaiah, Auteur Année de publication : 2009 Article en page(s) : pp. 3880–3897 Note générale : Chemical engineering Langues : Anglais (eng) Mots-clés : Hypnosis  Propofol  Bispectral  index  Nonlinear  PK−PD  representation Résumé : Anesthesia implies maintaining a triad of hypnosis, analgesia, and neuromuscular blockade by infusing several drugs which specifically act on each of the above aspects. This work focuses on controlling the hypnosis by automatic infusion of propofol using bispectral index (BIS) as the primary controlled variable. A fourth-order nonlinear pharmacokinetic (PK)−pharmacodynamic (PD) representation is used for the hypnosis dynamics of patients. A reliable PK−PD model with associated parameters is obtained from the literature and the closed-loop responses of four types of control strategies (model predictive control, internal model control, controller with modeling error compensation, and proportional-integral-derivative (PID) control) are compared. Robust performance of the four controllers is tested for a broad range of patients by considering variability in PK−PD parameters. Also, the relative performance of the four controllers is studied for different set-points, noise, and disturbances in BIS signal. Numerical simulations show that all the advanced controllers performed better than the PID controller with the model predictive controller showing the best performance. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie800695b [article] Advanced control strategies for the regulation of hypnosis with propofol [texte imprimé] / Yelneedi Sreenivas, Auteur ; Lakshminarayanan Samavedham, Auteur ; G.P. Rangaiah, Auteur . - 2009 . - pp. 3880–3897. Chemical engineering Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 48 N° 8 (Avril 2009) . - pp. 3880–3897 Mots-clés : Hypnosis  Propofol  Bispectral  index  Nonlinear  PK−PD  representation Résumé : Anesthesia implies maintaining a triad of hypnosis, analgesia, and neuromuscular blockade by infusing several drugs which specifically act on each of the above aspects. This work focuses on controlling the hypnosis by automatic infusion of propofol using bispectral index (BIS) as the primary controlled variable. A fourth-order nonlinear pharmacokinetic (PK)−pharmacodynamic (PD) representation is used for the hypnosis dynamics of patients. A reliable PK−PD model with associated parameters is obtained from the literature and the closed-loop responses of four types of control strategies (model predictive control, internal model control, controller with modeling error compensation, and proportional-integral-derivative (PID) control) are compared. Robust performance of the four controllers is tested for a broad range of patients by considering variability in PK−PD parameters. Also, the relative performance of the four controllers is studied for different set-points, noise, and disturbances in BIS signal. Numerical simulations show that all the advanced controllers performed better than the PID controller with the model predictive controller showing the best performance. En ligne : http://pubs.acs.org/doi/abs/10.1021/ie800695b

Comparative performance analysis of coordinated model predictive control schemes in the presence of model – plant mismatch / Abhay Anand in Industrial & engineering chemistry research, Vol. 51 N° 24 (Juin 2012) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 51 N° 24 (Juin 2012) . - pp. 8273-8285 Titre : Comparative performance analysis of coordinated model predictive control schemes in the presence of model – plant mismatch Type de document : texte imprimé Auteurs : Abhay Anand, Auteur ; Lakshminarayanan Samavedham, Auteur ; Sitanandam Sundaramoorthy, Auteur Année de publication : 2012 Article en page(s) : pp. 8273-8285 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Predictive  control  Modeling Résumé : Large-scale systems are formed by the interconnection of several subsystems, whose different spatial and temporal characteristics make them significantly heterogeneous. The optimal management of such systems must generally deal not only with issues related to large dimensionality and strong nonlinearity, but also with the presence of several interactions between the subsystems, which have a significant influence on the local control decisions and the overall system optimality. For such large-scale systems, model predictive control (MPC) is an attractive control strategy and can be implemented in centralized or decentralized configurations. It has been shown that, to achieve a flexible and reliable control structure with optimum overall system performance, individual decentralized controllers have to be coordinated and driven toward the performance of a centralized controller. In this work, three coordination strategies that have been reported in the literature, viz., communication based coordination, cooperation based coordination, and price driven coordination, are evaluated for controlling multivariable processes. These three strategies have been evaluated on a benchmark chemical engineering system and on a quadruple tank system (via simulations), on the basis of their robustness, stability, and performance in comparison to that of a centralized MPC implementation. The ability to deal with a variety of model uncertainties and the coordination between the controllers within and across a hierarchy are some important aspects that have been investigated. ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=26029662 [article] Comparative performance analysis of coordinated model predictive control schemes in the presence of model – plant mismatch [texte imprimé] / Abhay Anand, Auteur ; Lakshminarayanan Samavedham, Auteur ; Sitanandam Sundaramoorthy, Auteur . - 2012 . - pp. 8273-8285. Industrial chemistry Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 51 N° 24 (Juin 2012) . - pp. 8273-8285 Mots-clés : Predictive  control  Modeling Résumé : Large-scale systems are formed by the interconnection of several subsystems, whose different spatial and temporal characteristics make them significantly heterogeneous. The optimal management of such systems must generally deal not only with issues related to large dimensionality and strong nonlinearity, but also with the presence of several interactions between the subsystems, which have a significant influence on the local control decisions and the overall system optimality. For such large-scale systems, model predictive control (MPC) is an attractive control strategy and can be implemented in centralized or decentralized configurations. It has been shown that, to achieve a flexible and reliable control structure with optimum overall system performance, individual decentralized controllers have to be coordinated and driven toward the performance of a centralized controller. In this work, three coordination strategies that have been reported in the literature, viz., communication based coordination, cooperation based coordination, and price driven coordination, are evaluated for controlling multivariable processes. These three strategies have been evaluated on a benchmark chemical engineering system and on a quadruple tank system (via simulations), on the basis of their robustness, stability, and performance in comparison to that of a centralized MPC implementation. The ability to deal with a variety of model uncertainties and the coordination between the controllers within and across a hierarchy are some important aspects that have been investigated. ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=26029662

Review and analysis of blood glucose (BG) models for type 1 diabetic patients / Naviyn Prabhu Balakrishnan in Industrial & engineering chemistry research, Vol. 50 N° 21 (Novembre 2011) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 50 N° 21 (Novembre 2011) . - pp. 12041-12066 Titre : Review and analysis of blood glucose (BG) models for type 1 diabetic patients Type de document : texte imprimé Auteurs : Naviyn Prabhu Balakrishnan, Auteur ; Gade Pandu Rangaiah, Auteur ; Lakshminarayanan Samavedham, Auteur Année de publication : 2011 Article en page(s) : pp. 12041-12066 Note générale : Chimie industrielle Langues : Anglais (eng) Mots-clés : Modeling Résumé : Blood glucose (BG) regulation in type 1 diabetic patients has been investigated by researchers for a long time. Manv mathematical models mimicking the physiological behavior of diabetic patients have been developed to predict BG variations. Models characterizing meal absorption and physical activities have also been developed in the literature, as they play a significant role in altering BG levels. Hence, existing glucose-insulin dynamic models dating back from early 1960s are reviewed along with an overview of meal absorption and exercise effect models. The available knowledge-driven BG models have been classified into different families based on their origin for development. Also, five knowledge-driven BG models (with at least one model from a family) have been analyzed by either varying basal insulin or meal ingestion. The available meal absorption models have also been simulated to compare and analyze them for different meal sizes. The major objective of the analysis is to study the BG dynamics of different models at their nominal parameter values, under varying basal insulin doses and meal ingestion. Similar analysis has been performed on 10 adult patient models in a recent benchmark simulator for comparison. These results will be useful for understanding the responses of different BG models at their nominal parameter values and for preliminary selection of a suitable treatment model(s) for a patient. DEWEY : 660 ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=24697523 [article] Review and analysis of blood glucose (BG) models for type 1 diabetic patients [texte imprimé] / Naviyn Prabhu Balakrishnan, Auteur ; Gade Pandu Rangaiah, Auteur ; Lakshminarayanan Samavedham, Auteur . - 2011 . - pp. 12041-12066. Chimie industrielle Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 50 N° 21 (Novembre 2011) . - pp. 12041-12066 Mots-clés : Modeling Résumé : Blood glucose (BG) regulation in type 1 diabetic patients has been investigated by researchers for a long time. Manv mathematical models mimicking the physiological behavior of diabetic patients have been developed to predict BG variations. Models characterizing meal absorption and physical activities have also been developed in the literature, as they play a significant role in altering BG levels. Hence, existing glucose-insulin dynamic models dating back from early 1960s are reviewed along with an overview of meal absorption and exercise effect models. The available knowledge-driven BG models have been classified into different families based on their origin for development. Also, five knowledge-driven BG models (with at least one model from a family) have been analyzed by either varying basal insulin or meal ingestion. The available meal absorption models have also been simulated to compare and analyze them for different meal sizes. The major objective of the analysis is to study the BG dynamics of different models at their nominal parameter values, under varying basal insulin doses and meal ingestion. Similar analysis has been performed on 10 adult patient models in a recent benchmark simulator for comparison. These results will be useful for understanding the responses of different BG models at their nominal parameter values and for preliminary selection of a suitable treatment model(s) for a patient. DEWEY : 660 ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=24697523