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Biomimetic materials in tissue engineering / Jennifer Patterson in Materials today, Vol. 13 N° 1-2 (Janvier/Fevrier 2010) 

Public ISBD [article]  in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 14–22 Titre : Biomimetic materials in tissue engineering Type de document : texte imprimé Auteurs : Jennifer Patterson, Auteur ; Mikaël M. Martino, Auteur ; Jeffrey A. Hubbell, Auteur Année de publication : 2010 Article en page(s) : pp. 14–22 Note générale : Ingénierie Langues : Anglais (eng) Mots-clés : Molecules  Biomolecules  Biomimetic  materials  Chemical  schemes  Tissue  engineering Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Biomaterial matrices are being developed that mimic the key characteristics of the extracellular matrix, including presenting adhesion sites and displaying growth factors in the context of a viscoelastic hydrogel. This review focuses on two classes of materials: those that are derived from naturally occurring molecules and those that recapitulate key motifs of biomolecules within biologically active synthetic materials. For biologically derived materials, methods are being sought to gain molecular-level control over biological characteristics and biomechanics. For synthetic, biomimetic materials, chemical schemes are being developed to enable in situ cross-linking and protease-dependent degradation and release of incorporated growth factors. These materials will open new doors to biosurgical therapeutics in tissue engineering and regenerative medicine. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700134 [article] Biomimetic materials in tissue engineering [texte imprimé] / Jennifer Patterson, Auteur ; Mikaël M. Martino, Auteur ; Jeffrey A. Hubbell, Auteur . - 2010 . - pp. 14–22. Ingénierie Langues : Anglais (eng) in Materials today > Vol. 13 N° 1-2 (Janvier/Fevrier 2010) . - pp. 14–22 Mots-clés : Molecules  Biomolecules  Biomimetic  materials  Chemical  schemes  Tissue  engineering Index. décimale : 620 Essais des matériaux. Matériaux commerciaux. Station génératrice d'énergie. Economie de l'énergie Résumé : Biomaterial matrices are being developed that mimic the key characteristics of the extracellular matrix, including presenting adhesion sites and displaying growth factors in the context of a viscoelastic hydrogel. This review focuses on two classes of materials: those that are derived from naturally occurring molecules and those that recapitulate key motifs of biomolecules within biologically active synthetic materials. For biologically derived materials, methods are being sought to gain molecular-level control over biological characteristics and biomechanics. For synthetic, biomimetic materials, chemical schemes are being developed to enable in situ cross-linking and protease-dependent degradation and release of incorporated growth factors. These materials will open new doors to biosurgical therapeutics in tissue engineering and regenerative medicine. DEWEY : 620 ISSN : 1369-7021 En ligne : http://www.sciencedirect.com/science/article/pii/S1369702110700134