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Fabrication and characterization of PLLA /chitosan / nano calcium phosphate scaffolds by freeze - casting technique / Mahboubeh Jafarkhani in Industrial & engineering chemistry research, Vol. 51 N° 27 (Juillet 2012) 

Public ISBD [article]  in Industrial & engineering chemistry research > Vol. 51 N° 27 (Juillet 2012) . - pp. 9241-9249 Titre : Fabrication and characterization of PLLA /chitosan / nano calcium phosphate scaffolds by freeze - casting technique Type de document : texte imprimé Auteurs : Mahboubeh Jafarkhani, Auteur ; Alireza Fazlali, Auteur ; Fathollah Moztarzadeh, Auteur Année de publication : 2012 Article en page(s) : pp. 9241-9249 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Casting Résumé : In this research, nanocomposite scaffolds of chitosan/PLLA/nano calcium phosphate (average crystallite size of 16.5 nm) have been prepared via the freeze-casting method and then characterized. The effects of nano powder contents on the structure of scaffolds were investigated to provide an appropriate nanocomposite for bone tissue engineering applications. The results showed that the scaffolds had high porosity (up to 98%) with open pores of 80-380 μm in diameter. It was also shown that the porosity increased with decreasing nano powder content. Furthermore, the bioactive nano calcium phosphate was homogenously distributed within the polymeric matrix of scaffolds, which contained up to 40% of nano powder. Microstructure studies showed that the pores were distributed very well throughout the structures. This macropores structure with interconnected pores provides the properties of scaffolds required for bone tissue engineering applications. ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=26132260 [article] Fabrication and characterization of PLLA /chitosan / nano calcium phosphate scaffolds by freeze - casting technique [texte imprimé] / Mahboubeh Jafarkhani, Auteur ; Alireza Fazlali, Auteur ; Fathollah Moztarzadeh, Auteur . - 2012 . - pp. 9241-9249. Industrial chemistry Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 51 N° 27 (Juillet 2012) . - pp. 9241-9249 Mots-clés : Casting Résumé : In this research, nanocomposite scaffolds of chitosan/PLLA/nano calcium phosphate (average crystallite size of 16.5 nm) have been prepared via the freeze-casting method and then characterized. The effects of nano powder contents on the structure of scaffolds were investigated to provide an appropriate nanocomposite for bone tissue engineering applications. The results showed that the scaffolds had high porosity (up to 98%) with open pores of 80-380 μm in diameter. It was also shown that the porosity increased with decreasing nano powder content. Furthermore, the bioactive nano calcium phosphate was homogenously distributed within the polymeric matrix of scaffolds, which contained up to 40% of nano powder. Microstructure studies showed that the pores were distributed very well throughout the structures. This macropores structure with interconnected pores provides the properties of scaffolds required for bone tissue engineering applications. ISSN : 0888-5885 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=26132260