Documents disponibles écrits par cet auteur

Bergamot (Citrus bergamia Risso et Poiteau) essential oil / Paul Forlot in The journal of essential oil research, Vol. 24 N° 2 (Avril 2012) 

Public ISBD [article]  in The journal of essential oil research > Vol. 24 N° 2 (Avril 2012) . - pp. 195-201 Titre : Bergamot (Citrus bergamia Risso et Poiteau) essential oil : Biological properties, cosmetic and medical use. A review Type de document : texte imprimé Auteurs : Paul Forlot, Auteur ; Paul Pevet, Auteur Année de publication : 2012 Article en page(s) : pp. 195-201 Note générale : Génie Chimique Langues : Anglais (eng) Mots-clés : Citrus  bergamia  Bergamot  oil  Bergapten  Phototoxicity  Photoprotection  Photogenotoxicity  DNA  photoaddition  Photochemotherapy  Dermatoses  Melatonin  sleep  disorders  Depression  Potassium  channels  blockers  Demyelinating  diseases  Anti-inflammatory  and  antimicrobial  properties Résumé : The present article reviews all aspects of the known pharmacological activities of bergamot essential oil (Citrus bergamia) and of its major phototoxic component bergapten (5-methoxypsoralen, 5-MOP) as well as their use in cosmetics and medicine. Photo-addition of 5-MOP to DNA induces a phototoxic reaction followed by significant increase of human skin pigmentation with a proved consistent protection of epidermal cell DNA against further exposure to ultraviolet light. This property was used in suntan products, but the potential risk of photocarcinogenis stopped the development of such compositions. Medical indications include phototherapy of dermatoses like psoriasis and vitiligo (photochemotherapy, PUVA). More recent studies were developed concerning the melatoninergic potential of bergapten and its potential use in depression and sleep disturbances as well as the capacity of 5-MOP to block potassium channels, a potential symptomatic treatment of multiple sclerosis in demyelinated nerves. The anti-inflammatory, antibacterial and antifungal properties of bergamot oil will also be described as well as the most recent studies on its protection against neuropathic pain in cancer. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/full/10.1080/10412905.2012.659527 [article] Bergamot (Citrus bergamia Risso et Poiteau) essential oil : Biological properties, cosmetic and medical use. A review [texte imprimé] / Paul Forlot, Auteur ; Paul Pevet, Auteur . - 2012 . - pp. 195-201. Génie Chimique Langues : Anglais (eng) in The journal of essential oil research > Vol. 24 N° 2 (Avril 2012) . - pp. 195-201 Mots-clés : Citrus  bergamia  Bergamot  oil  Bergapten  Phototoxicity  Photoprotection  Photogenotoxicity  DNA  photoaddition  Photochemotherapy  Dermatoses  Melatonin  sleep  disorders  Depression  Potassium  channels  blockers  Demyelinating  diseases  Anti-inflammatory  and  antimicrobial  properties Résumé : The present article reviews all aspects of the known pharmacological activities of bergamot essential oil (Citrus bergamia) and of its major phototoxic component bergapten (5-methoxypsoralen, 5-MOP) as well as their use in cosmetics and medicine. Photo-addition of 5-MOP to DNA induces a phototoxic reaction followed by significant increase of human skin pigmentation with a proved consistent protection of epidermal cell DNA against further exposure to ultraviolet light. This property was used in suntan products, but the potential risk of photocarcinogenis stopped the development of such compositions. Medical indications include phototherapy of dermatoses like psoriasis and vitiligo (photochemotherapy, PUVA). More recent studies were developed concerning the melatoninergic potential of bergapten and its potential use in depression and sleep disturbances as well as the capacity of 5-MOP to block potassium channels, a potential symptomatic treatment of multiple sclerosis in demyelinated nerves. The anti-inflammatory, antibacterial and antifungal properties of bergamot oil will also be described as well as the most recent studies on its protection against neuropathic pain in cancer. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/full/10.1080/10412905.2012.659527