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Détail de l'auteur
Auteur Randy D. Weinstein
Documents disponibles écrits par cet auteur
Affiner la rechercheLiquid and supercritical carbon dioxide - assisted implantation of ketoprofen into biodegradable sutures / Randy D. Weinstein in Industrial & engineering chemistry research, Vol. 49 N° 16 (Août 2010)
[article]
in Industrial & engineering chemistry research > Vol. 49 N° 16 (Août 2010) . - pp. 7281–7286
Titre : Liquid and supercritical carbon dioxide - assisted implantation of ketoprofen into biodegradable sutures Type de document : texte imprimé Auteurs : Randy D. Weinstein, Auteur ; Kenneth R. Muske, Auteur ; Sherrie-Ann Martin, Auteur Année de publication : 2010 Article en page(s) : pp. 7281–7286 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Carbon Dioxide Biodegradable Résumé : In this study we explored the use of liquid and supercritical carbon dioxide for the creation of a sustained release drug delivery device. An anti-inflammatory (ketoprofen) was dissolved into carbon dioxide at various temperatures (25−55 °C) and pressures (65−300 bar) and then exposed to biodegradable braided sutures made of poly(lactide-co-glycolide) copolymers. The effect of temperature, pressure (and hence density), and exposure time were explored on the ability of the sutures to absorb ketoprofen. The diffusion of the drug into the suture was modeled, and diffusion coefficients were calculated. The amount of ketoprofen loaded into the suture increased with pressure and density and decreased with temperature; however, increasing temperature tended to speed up the absorption process. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie901913x [article] Liquid and supercritical carbon dioxide - assisted implantation of ketoprofen into biodegradable sutures [texte imprimé] / Randy D. Weinstein, Auteur ; Kenneth R. Muske, Auteur ; Sherrie-Ann Martin, Auteur . - 2010 . - pp. 7281–7286.
Industrial chemistry
Langues : Anglais (eng)
in Industrial & engineering chemistry research > Vol. 49 N° 16 (Août 2010) . - pp. 7281–7286
Mots-clés : Carbon Dioxide Biodegradable Résumé : In this study we explored the use of liquid and supercritical carbon dioxide for the creation of a sustained release drug delivery device. An anti-inflammatory (ketoprofen) was dissolved into carbon dioxide at various temperatures (25−55 °C) and pressures (65−300 bar) and then exposed to biodegradable braided sutures made of poly(lactide-co-glycolide) copolymers. The effect of temperature, pressure (and hence density), and exposure time were explored on the ability of the sutures to absorb ketoprofen. The diffusion of the drug into the suture was modeled, and diffusion coefficients were calculated. The amount of ketoprofen loaded into the suture increased with pressure and density and decreased with temperature; however, increasing temperature tended to speed up the absorption process. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie901913x Quantification of the impact of embedded graphite nanofibers on the transient thermal response of paraffin phase change material exposed to high heat fluxes / Kireeti Chintakrinda in Journal of heat transfer, Vol. 134 N° 7 (Juillet 2012)
[article]
in Journal of heat transfer > Vol. 134 N° 7 (Juillet 2012) . - 10 p.
Titre : Quantification of the impact of embedded graphite nanofibers on the transient thermal response of paraffin phase change material exposed to high heat fluxes Type de document : texte imprimé Auteurs : Kireeti Chintakrinda, Auteur ; Ronald J. Warzoha, Auteur ; Randy D. Weinstein, Auteur Année de publication : 2012 Article en page(s) : 10 p. Note générale : heat transfer Langues : Anglais (eng) Mots-clés : melting and solidifaction; electronics cooling Index. décimale : 536 Chaleur. Thermodynamique Résumé : Paraffin phase change material (PCM) is enhanced with suspended graphite nanofibers at high loading levels. The loading levels reach in excess of 10% by weight. The thermal effects of the nanofiber loading level, the PCM module design, and the applied power density on the transient thermal response of the system are examined. A strong effect of nanofiber loading level on thermal performance is found, including a suppression of Rayleigh-Benard convection currents at high loading levels. Increases in nanofiber loading level also result in lowered heating rates and greater thermal control of the heated base. Increases in power density are found to result in higher heating rates, and increases in mass lead to lower operating temperatures. The design of the module is found to have a strong effect on thermal performance. DEWEY : 536 ISSN : 0022-1481 En ligne : http://asmedl.org/getabs/servlet/GetabsServlet?prog=normal&id=JHTRAO000134000007 [...] [article] Quantification of the impact of embedded graphite nanofibers on the transient thermal response of paraffin phase change material exposed to high heat fluxes [texte imprimé] / Kireeti Chintakrinda, Auteur ; Ronald J. Warzoha, Auteur ; Randy D. Weinstein, Auteur . - 2012 . - 10 p.
heat transfer
Langues : Anglais (eng)
in Journal of heat transfer > Vol. 134 N° 7 (Juillet 2012) . - 10 p.
Mots-clés : melting and solidifaction; electronics cooling Index. décimale : 536 Chaleur. Thermodynamique Résumé : Paraffin phase change material (PCM) is enhanced with suspended graphite nanofibers at high loading levels. The loading levels reach in excess of 10% by weight. The thermal effects of the nanofiber loading level, the PCM module design, and the applied power density on the transient thermal response of the system are examined. A strong effect of nanofiber loading level on thermal performance is found, including a suppression of Rayleigh-Benard convection currents at high loading levels. Increases in nanofiber loading level also result in lowered heating rates and greater thermal control of the heated base. Increases in power density are found to result in higher heating rates, and increases in mass lead to lower operating temperatures. The design of the module is found to have a strong effect on thermal performance. DEWEY : 536 ISSN : 0022-1481 En ligne : http://asmedl.org/getabs/servlet/GetabsServlet?prog=normal&id=JHTRAO000134000007 [...]