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Commercial zinc oxide : A facile, efficient, and Eco-friendly catalyst for the one-pot three-component synthesis of multisubstituted 2-aminothiophenes via the gewald reaction

Reza Tayebee, Auteur ; S. Javad Ahmadi, Auteur ; Esmaeil Rezaei Seresht, Auteur |

Dans Industrial & engineering chemistry research (Vol. 51 N° 44, Novembre 2012)

An eco-friendly, simple, and effective protocol is developed for the synthesis of various multisubstituted 2-aminothiophenes. In the presence of a catalytic amount of ZnO (5 mol %), ketones or aldehydes, malononitrile and elemental sulfur were c[...]

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