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Chemical composition, mutagenic and antimutagenic activities of essential oils from (Tunisian) artemisia campestris and artemisia herba-alba / Aicha Neffati in The journal of essential oil research, Vol. 20 N°5 (Septembre/Octobre 2008) 

Public ISBD [article]  in The journal of essential oil research > Vol. 20 N°5 (Septembre/Octobre 2008) . - pp. 471-477 Titre : Chemical composition, mutagenic and antimutagenic activities of essential oils from (Tunisian) artemisia campestris and artemisia herba-alba Type de document : texte imprimé Auteurs : Aicha Neffati, Auteur ; Ines Skandrani, Auteur ; Mohamed Ben Sghaier, Auteur Année de publication : 2008 Article en page(s) : pp. 471-477 Note générale : Génie Chimique Langues : Anglais (eng) Mots-clés : Artemisia  campestris  Artemisia  herba-alba  Asteraceae  Essential  oil  β-pinene  Pinocarvone  α-copaene  Limonene  Isoamyl-2-méthylbutyrate  Mutagenicity  Antimutagenicity  Ames  test Résumé : The essential oil composition from the aerial parts of Artemisia campestris var. glutinosa Gay ex Bess and Artemisia herba-alba Asso (Asteraceae) of Tunisian origin has been studied by GC and GC/MS. The main constituents of the oil from A. campestris collected in Benguerdane (South of Tunisia) were found to be β-pinene (41.0%), p-cymene (9.9%), α-terpinene (7.9%), limonene (6.5%), myrcene (4.1%), β-phellandrene (3.4%) and a-pinene (3.2%). Whereas the oil from A. herba-alba collected in Tataouine (South of Tunisia) showed, pinocarvone (38.3%), a-copaene (12.18%), limonene (11.0%), isoamyl2-methylbutyrate (19.5%) as major compounds. The mutagenic and antimutagenic activities of the two oils were investigated by the Salmonella typhimurium/microsome assay, with and without addition of an extrinsic metabolic activation system. The oils showed no mutagenicity when tested with Salmonella typhimurium strains TA98 and TA97. On the other hand, we showed that each oil had antimutagenic activity against the carcinogen Benzo (a) pyrene (B[a] P) when tested with TA97 and TA98 assay systems. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/abs/10.1080/10412905.2008.9700061 [article] Chemical composition, mutagenic and antimutagenic activities of essential oils from (Tunisian) artemisia campestris and artemisia herba-alba [texte imprimé] / Aicha Neffati, Auteur ; Ines Skandrani, Auteur ; Mohamed Ben Sghaier, Auteur . - 2008 . - pp. 471-477. Génie Chimique Langues : Anglais (eng) in The journal of essential oil research > Vol. 20 N°5 (Septembre/Octobre 2008) . - pp. 471-477 Mots-clés : Artemisia  campestris  Artemisia  herba-alba  Asteraceae  Essential  oil  β-pinene  Pinocarvone  α-copaene  Limonene  Isoamyl-2-méthylbutyrate  Mutagenicity  Antimutagenicity  Ames  test Résumé : The essential oil composition from the aerial parts of Artemisia campestris var. glutinosa Gay ex Bess and Artemisia herba-alba Asso (Asteraceae) of Tunisian origin has been studied by GC and GC/MS. The main constituents of the oil from A. campestris collected in Benguerdane (South of Tunisia) were found to be β-pinene (41.0%), p-cymene (9.9%), α-terpinene (7.9%), limonene (6.5%), myrcene (4.1%), β-phellandrene (3.4%) and a-pinene (3.2%). Whereas the oil from A. herba-alba collected in Tataouine (South of Tunisia) showed, pinocarvone (38.3%), a-copaene (12.18%), limonene (11.0%), isoamyl2-methylbutyrate (19.5%) as major compounds. The mutagenic and antimutagenic activities of the two oils were investigated by the Salmonella typhimurium/microsome assay, with and without addition of an extrinsic metabolic activation system. The oils showed no mutagenicity when tested with Salmonella typhimurium strains TA98 and TA97. On the other hand, we showed that each oil had antimutagenic activity against the carcinogen Benzo (a) pyrene (B[a] P) when tested with TA97 and TA98 assay systems. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/abs/10.1080/10412905.2008.9700061