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Clastogenic and anticlastogenic effect of the essential oil from casearia sylvestris swart. / Fabrício G. Sousa in The journal of essential oil research, Vol. 19 N°4 (Juillet/Août 2007) 

Public ISBD [article]  in The journal of essential oil research > Vol. 19 N°4 (Juillet/Août 2007) . - pp. 376-378 Titre : Clastogenic and anticlastogenic effect of the essential oil from casearia sylvestris swart. Type de document : texte imprimé Auteurs : Fabrício G. Sousa, Auteur ; Naira F.Z. Schneider, Auteur ; Caroline E. Mendes, Auteur Année de publication : 2007 Article en page(s) : pp. 376-378 Note générale : Génie Chimique Langues : Anglais (eng) Mots-clés : Casearia  sylvestris  Flacourtiaceae  Essential  oil  composition  β-caryophyllene  Clastogenic  activity  Anticlastogenic  activity Résumé : The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in the oil. The major constituents of which were β-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic effect of the oil was tested by chromosome aberration in cells of tissue hepatoma of Rattus novergicus. The three different concentrations of C. sylvestris oil showed clastogenic effects. However, in the tests of anticlastogenicity, the same three concentrations showed protective activity when associated with ethyl methanesulfonate (EMS). ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/abs/10.1080/10412905.2007.9699309#.UW5WDkqC5mN [article] Clastogenic and anticlastogenic effect of the essential oil from casearia sylvestris swart. [texte imprimé] / Fabrício G. Sousa, Auteur ; Naira F.Z. Schneider, Auteur ; Caroline E. Mendes, Auteur . - 2007 . - pp. 376-378. Génie Chimique Langues : Anglais (eng) in The journal of essential oil research > Vol. 19 N°4 (Juillet/Août 2007) . - pp. 376-378 Mots-clés : Casearia  sylvestris  Flacourtiaceae  Essential  oil  composition  β-caryophyllene  Clastogenic  activity  Anticlastogenic  activity Résumé : The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in the oil. The major constituents of which were β-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic effect of the oil was tested by chromosome aberration in cells of tissue hepatoma of Rattus novergicus. The three different concentrations of C. sylvestris oil showed clastogenic effects. However, in the tests of anticlastogenicity, the same three concentrations showed protective activity when associated with ethyl methanesulfonate (EMS). ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/abs/10.1080/10412905.2007.9699309#.UW5WDkqC5mN