Biological activities and composition of Salvia muirii L. bol. essential oil / Guy P. P. Kamatou in The journal of essential oil research, Vol. 18 N° Spécial (Juillet 2006)  

Public ISBD [article]  inThe journal of essential oil research > Vol. 18 N° Spécial (Juillet 2006) . - pp. 48-51 Titre : Biological activities and composition of Salvia muirii L. bol. essential oil Type de document : texte imprimé Auteurs : Guy P. P. Kamatou, Auteur ; Robyn L. Vanzyl, Auteur ; Sandy F. Van Vuuren, Auteur Année de publication : 2013 Article en page(s) : pp. 48-51 Note générale : Génie Chimique Langues : Anglais (eng) Mots-clés : Salvia muirii Lamiaceae Biological activities Essential oil composition α  -pinene 1,8-cineole Limonene Antimicrobial activity Anti-inflammatory Antimalarial Antioxidant Toxicity Résumé : The essential oil of Salvia muirii L. Bol., a species indigenous to southern Africa was obtained by hydrodistillation (0.5%, v/f.w.) from the aerial parts and analyzed by GC and GC/MS. Thirty-nine components representing 98% of the oil were identified. The oil was dominated by monoterpene hydrocarbons (53%) and oxygen-containing monoterpenes (36%) with 1,8-cineole (23%), α-pinene (22%) and limonene (12%) being the major components. The oil exhibited potent antimalarial (IC50: 6μg/mL) and antibacterial activity especially against Klebsiella pneumoniae and Bacillus cereus with MIC values of 6 and 9mg/mL, respectively. The oil exhibited poor anti-inflammatory and antioxidant activity. The 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide toxicity assay revealed that the essential oil of S. muirii should be used with caution as it displayed some degree of toxicity against the transformed human kidney epithelial cells (IC50: 3μg/mL). ISSN : 1041-2905 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=18019081 [article] Biological activities and composition of Salvia muirii L. bol. essential oil [texte imprimé] / Guy P. P. Kamatou, Auteur ; Robyn L. Vanzyl, Auteur ; Sandy F. Van Vuuren, Auteur . - 2013 . - pp. 48-51. Génie Chimique Langues : Anglais (eng) in The journal of essential oil research > Vol. 18 N° Spécial (Juillet 2006) . - pp. 48-51 Mots-clés : Salvia muirii Lamiaceae Biological activities Essential oil composition α  -pinene 1,8-cineole Limonene Antimicrobial activity Anti-inflammatory Antimalarial Antioxidant Toxicity Résumé : The essential oil of Salvia muirii L. Bol., a species indigenous to southern Africa was obtained by hydrodistillation (0.5%, v/f.w.) from the aerial parts and analyzed by GC and GC/MS. Thirty-nine components representing 98% of the oil were identified. The oil was dominated by monoterpene hydrocarbons (53%) and oxygen-containing monoterpenes (36%) with 1,8-cineole (23%), α-pinene (22%) and limonene (12%) being the major components. The oil exhibited potent antimalarial (IC50: 6μg/mL) and antibacterial activity especially against Klebsiella pneumoniae and Bacillus cereus with MIC values of 6 and 9mg/mL, respectively. The oil exhibited poor anti-inflammatory and antioxidant activity. The 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide toxicity assay revealed that the essential oil of S. muirii should be used with caution as it displayed some degree of toxicity against the transformed human kidney epithelial cells (IC50: 3μg/mL). ISSN : 1041-2905 En ligne : http://cat.inist.fr/?aModele=afficheN&cpsidt=18019081

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