Fabrication of biocompatible temperature- and pH-responsive magnetic nanoparticles and their reversible agglomeration in aqueous milieu / Liangrong Yang in Industrial & engineering chemistry research, Vol. 49 N° 18 (Septembre 2010)  

Public ISBD [article]  inIndustrial & engineering chemistry research > Vol. 49 N° 18 (Septembre 2010) . - pp. 8518–8525 Titre : Fabrication of biocompatible temperature- and pH-responsive magnetic nanoparticles and their reversible agglomeration in aqueous milieu Type de document : texte imprimé Auteurs : Liangrong Yang, Auteur ; Chen Guo, Auteur ; Lianwei Jia, Auteur Année de publication : 2010 Article en page(s) : pp. 8518–8525 Note générale : Industrial chemistry Langues : Anglais (eng) Mots-clés : Nanoparticles Aqueous milieu Résumé : A novel kind of biocompatible pH- and temperature-responsive magnetic nanoparticle consisting of iron oxide nanoparticles coated with pH-responsive chitosan oligosaccharide and temperature-responsive poly(ethylene oxide)−poly(propylene oxide)−poly(ethylene oxide) block copolymer was developed. The particles were characterized by TEM, DLS, VSM, FTIR spectroscopy, and TGA. The results indicated that the self-aggregation of the prepared nanoparticles was not only caused by the thermoinduced self-assembly of the immobilized block copolymers, but also affected by the pH-induced charge property change of the particle surface. The self-assembled behaviors can be readily reversed by adjusting the pH or temperature value. Thus, the attractive properties of reversible and controllable dual-responsive self-assembly might endow the biocompatible magnetic nanoparticles with potential applications in biomedical fields such as DNA delivery, drug targeting, and tissue engineering. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie100587e [article] Fabrication of biocompatible temperature- and pH-responsive magnetic nanoparticles and their reversible agglomeration in aqueous milieu [texte imprimé] / Liangrong Yang, Auteur ; Chen Guo, Auteur ; Lianwei Jia, Auteur . - 2010 . - pp. 8518–8525. Industrial chemistry Langues : Anglais (eng) in Industrial & engineering chemistry research > Vol. 49 N° 18 (Septembre 2010) . - pp. 8518–8525 Mots-clés : Nanoparticles Aqueous milieu Résumé : A novel kind of biocompatible pH- and temperature-responsive magnetic nanoparticle consisting of iron oxide nanoparticles coated with pH-responsive chitosan oligosaccharide and temperature-responsive poly(ethylene oxide)−poly(propylene oxide)−poly(ethylene oxide) block copolymer was developed. The particles were characterized by TEM, DLS, VSM, FTIR spectroscopy, and TGA. The results indicated that the self-aggregation of the prepared nanoparticles was not only caused by the thermoinduced self-assembly of the immobilized block copolymers, but also affected by the pH-induced charge property change of the particle surface. The self-assembled behaviors can be readily reversed by adjusting the pH or temperature value. Thus, the attractive properties of reversible and controllable dual-responsive self-assembly might endow the biocompatible magnetic nanoparticles with potential applications in biomedical fields such as DNA delivery, drug targeting, and tissue engineering. ISSN : 0888-5885 En ligne : http://pubs.acs.org/doi/abs/10.1021/ie100587e

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