Essential oils from baccharis species (Asteraceae) have anti-inflammatory effects for human cells / Angela Florão in The journal of essential oil research, Vol. 24 N° 6 (Décembre 2012)  

Public ISBD [article]  inThe journal of essential oil research > Vol. 24 N° 6 (Décembre 2012) . - pp. 561-570 Titre : Essential oils from baccharis species (Asteraceae) have anti-inflammatory effects for human cells Type de document : texte imprimé Auteurs : Angela Florão, Auteur ; Jane Manfrom Budel, Auteur ; Marcia do Rocio Duarte, Auteur Année de publication : 2014 Article en page(s) : pp. 561-570 Note générale : Génie Chimique Langues : Anglais (eng) Mots-clés : Baccharis Asteraceae Essential oil composition Spathulenol immunomodulation Chemotaxis Résumé : Constituents of the essential oils from the aerial parts of Baccharis articulata (Ba), Baccharis genistelloides subsp. crispa (Bc), Baccharis dracunculifolia (Bd) and Baccharis gaudichaudiana (Bg), Asteraceae, obtained by hydrodistillation and analyzed by gas chromatography (GC)/mass spectrometry (MS) and GC/flame ionization detector (FID) were identified. Also, their anti-inflammatory potential, focusing their immunomodulatory activity using flow cytometric analyses and AgNOR profiles, and anti-chemotactic properties, conducted using a Boyden’s chamber system, were investigated. Fifty-eight compounds were characterized, representing 66.7% of the total components detected. The major constituents identified were spathulenol (in Ba, Bd and Bg), τ-gurjunene (in Bg) and palustrol (in Ba). The data presented herein showed that the Baccharis essential oils included in this study were inert for human resting lymphocytes, while all but Ba’s inhibited significantly the proliferation of their phytohemagglutinin-stimulated counterparts. In addition, only the essential oil of Bd inhibited significantly the casein-induced human granulocyte chemotaxis. This is the first report concerning the potential diversity of anti-inflammatory activities of the essential oils of Baccharis plants on human cells responsible for the host defense mechanisms that may be of benefit in intervening with immune disorders associated or not with inflammatory conditions. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/full/10.1080/10412905.2012.728081 [article] Essential oils from baccharis species (Asteraceae) have anti-inflammatory effects for human cells [texte imprimé] / Angela Florão, Auteur ; Jane Manfrom Budel, Auteur ; Marcia do Rocio Duarte, Auteur . - 2014 . - pp. 561-570. Génie Chimique Langues : Anglais (eng) in The journal of essential oil research > Vol. 24 N° 6 (Décembre 2012) . - pp. 561-570 Mots-clés : Baccharis Asteraceae Essential oil composition Spathulenol immunomodulation Chemotaxis Résumé : Constituents of the essential oils from the aerial parts of Baccharis articulata (Ba), Baccharis genistelloides subsp. crispa (Bc), Baccharis dracunculifolia (Bd) and Baccharis gaudichaudiana (Bg), Asteraceae, obtained by hydrodistillation and analyzed by gas chromatography (GC)/mass spectrometry (MS) and GC/flame ionization detector (FID) were identified. Also, their anti-inflammatory potential, focusing their immunomodulatory activity using flow cytometric analyses and AgNOR profiles, and anti-chemotactic properties, conducted using a Boyden’s chamber system, were investigated. Fifty-eight compounds were characterized, representing 66.7% of the total components detected. The major constituents identified were spathulenol (in Ba, Bd and Bg), τ-gurjunene (in Bg) and palustrol (in Ba). The data presented herein showed that the Baccharis essential oils included in this study were inert for human resting lymphocytes, while all but Ba’s inhibited significantly the proliferation of their phytohemagglutinin-stimulated counterparts. In addition, only the essential oil of Bd inhibited significantly the casein-induced human granulocyte chemotaxis. This is the first report concerning the potential diversity of anti-inflammatory activities of the essential oils of Baccharis plants on human cells responsible for the host defense mechanisms that may be of benefit in intervening with immune disorders associated or not with inflammatory conditions. ISSN : 1041-2905 En ligne : http://www.tandfonline.com/doi/full/10.1080/10412905.2012.728081

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