Article : texte imprimé

Use of “bricks and mortar” model to predict transdermal permeation : model development and initial validation

Longjian Chen, Auteur ; Guoping Lian, Auteur ; Lujia Han, Auteur |

Dans Industrial & engineering chemistry research (Vol. 47 N°17, Septembre 2008)

Presented in this paper is a general purpose computer model for predicting transdermal permeation of solutes in vivo. The “bricks and mortar” model is employed to represent the stratum corneum (SC), the main barrier to transdermal permeation. Tr[...]

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