High throughput methodology for continuous preparation of hydroxyapatite nanoparticles in a microporous tube-in-tube microchannel reactor / Qing Yang in Industrial & engineering chemistry research, Vol. 49 N° 1 (Janvier 2010)  

High throughput methodology for continuous preparation of hydroxyapatite nanoparticles in a microporous tube-in-tube microchannel reactor [texte imprimé] / Qing Yang, Auteur ; Jie-Xin Wang, Auteur ; Lei Shao, Auteur . - 2010 . - pp. 140–147.
Industrial chemistry
Langues : Anglais (eng)
in Industrial & engineering chemistry research > Vol. 49 N° 1 (Janvier 2010) . - pp. 140–147

Mots-clés :	Throughput--Methodology--Continuous--Hydroxyapatite--Nanoparticles--Microporous--Tube-in-Tube--Microchannel Reactor
Résumé :	A microporous tube-in-tube microchannel reactor (MTMCR) was successfully adopted to prepare hydroxyapatite (HAP) nanoparticles. The rodlike HAP nanoparticles with a mean size of 58 nm, a specific surface area of 49.32 m2/g, and a narrow size distribution were obtained in an MTMCR under a high throughput of 3 L/min. The mean particle size sharply decreased with increasing the continuous phase flow rate, while first decreased and subsequently increased with increasing the dispersed phase flow rate and the reactant concentration. The extension of the mixing distance led to the initial rapid and following slight decrease of the mean particle size. The size of HAP nanoparticles was also strongly dependent on the micropore size on the surface of inner tube. Small micropore size was beneficial for producing small particles. For comparison, HAP nanoparticles were also prepared in a stirred tank reactor (STR) and a T-junction microchannel reactor (TMCR), clearly exhibiting the advantages of the MTMCR over the STR and TMCR due to the achievement of uniformly smaller HAP nanoparticles and a high throughput for industrial production.
ISSN :	0888-5885
En ligne :	http://pubs.acs.org/doi/abs/10.1021/ie9005436